Mastering Organic Synthesis with 3-Fluoro-4-nitrotoluene
Organic synthesis is the cornerstone of modern chemistry, enabling the creation of new molecules that drive innovation across industries from pharmaceuticals to materials science. The efficiency and success of any synthetic endeavor often depend on the quality and reactivity of the starting materials and intermediates used. 3-Fluoro-4-nitrotoluene (CAS No. 446-34-4) is a prime example of such a critical organic intermediate, offering chemists a powerful tool for molecular construction. NINGBO INNO PHARMCHEM CO.,LTD. is a leading provider of this essential chemical building block in China.
Characterized by its off-white to pale yellow crystalline powder form, 3-Fluoro-4-nitrotoluene possesses a molecular formula of C7H6FNO2 and a molecular weight of 155.13 g/mol. Its significance in organic synthesis stems from the strategic placement of a fluorine atom and a nitro group on a toluene ring. These functional groups impart specific electronic and steric properties that govern its reactivity in various transformations, such as nucleophilic aromatic substitutions, reduction of the nitro group, and palladium-catalyzed cross-coupling reactions.
Chemists leverage 3-Fluoro-4-nitrotoluene for its ability to introduce specific structural motifs into target molecules. For example, the nitro group can be reduced to an amine, which is a common functional handle for further elaboration, such as amide formation or diazotization. The fluorine atom can influence the lipophilicity, metabolic stability, and binding affinity of pharmaceutical candidates, making it a valuable substituent in drug design.
The compound's melting point of 52-55 °C and boiling point of 97-98 °C (at 3 mm Hg) provide a good indication of its handling characteristics and suitability for different reaction temperatures. Researchers can confidently purchase 3-Fluoro-4-nitrotoluene from NINGBO INNO PHARMCHEM CO.,LTD. knowing they are acquiring a high-purity (≥98%) intermediate. This high purity is crucial for achieving predictable reaction outcomes and minimizing side products in complex synthetic sequences.
Whether you are developing novel pharmaceuticals, advanced materials, or specialized agrochemicals, incorporating 3-Fluoro-4-nitrotoluene into your synthetic strategy can unlock new possibilities. NINGBO INNO PHARMCHEM CO.,LTD. is your trusted partner for sourcing this indispensable organic synthesis intermediate, ensuring the quality and reliability needed to advance your chemical research and production goals.
Characterized by its off-white to pale yellow crystalline powder form, 3-Fluoro-4-nitrotoluene possesses a molecular formula of C7H6FNO2 and a molecular weight of 155.13 g/mol. Its significance in organic synthesis stems from the strategic placement of a fluorine atom and a nitro group on a toluene ring. These functional groups impart specific electronic and steric properties that govern its reactivity in various transformations, such as nucleophilic aromatic substitutions, reduction of the nitro group, and palladium-catalyzed cross-coupling reactions.
Chemists leverage 3-Fluoro-4-nitrotoluene for its ability to introduce specific structural motifs into target molecules. For example, the nitro group can be reduced to an amine, which is a common functional handle for further elaboration, such as amide formation or diazotization. The fluorine atom can influence the lipophilicity, metabolic stability, and binding affinity of pharmaceutical candidates, making it a valuable substituent in drug design.
The compound's melting point of 52-55 °C and boiling point of 97-98 °C (at 3 mm Hg) provide a good indication of its handling characteristics and suitability for different reaction temperatures. Researchers can confidently purchase 3-Fluoro-4-nitrotoluene from NINGBO INNO PHARMCHEM CO.,LTD. knowing they are acquiring a high-purity (≥98%) intermediate. This high purity is crucial for achieving predictable reaction outcomes and minimizing side products in complex synthetic sequences.
Whether you are developing novel pharmaceuticals, advanced materials, or specialized agrochemicals, incorporating 3-Fluoro-4-nitrotoluene into your synthetic strategy can unlock new possibilities. NINGBO INNO PHARMCHEM CO.,LTD. is your trusted partner for sourcing this indispensable organic synthesis intermediate, ensuring the quality and reliability needed to advance your chemical research and production goals.
Perspectives & Insights
Silicon Analyst 88
“The efficiency and success of any synthetic endeavor often depend on the quality and reactivity of the starting materials and intermediates used.”
Quantum Seeker Pro
“446-34-4) is a prime example of such a critical organic intermediate, offering chemists a powerful tool for molecular construction.”
Bio Reader 7
“Characterized by its off-white to pale yellow crystalline powder form, 3-Fluoro-4-nitrotoluene possesses a molecular formula of C7H6FNO2 and a molecular weight of 155.”