In the intricate world of organic chemistry and pharmaceutical development, precision and purity are paramount. For researchers and manufacturers focused on peptide synthesis, understanding the critical role of chiral intermediates is essential. Among these, L-Leucine N-carboxyanhydride (L-Leu-NCA), also known by its CAS number 3190-70-3 and its IUPAC name (S)-4-Isobutyloxazolidine-2,5-dione, stands out as a versatile and indispensable building block. As a leading supplier, we are dedicated to providing researchers with this high-quality compound to advance their groundbreaking work.

The synthesis of peptides, the molecular chains that form the basis of proteins and many vital biological functions, requires careful stepwise addition of amino acids. L-Leu-NCA is a highly reactive derivative of the amino acid L-leucine, prepared in a form that allows for efficient coupling. Its key advantage lies in its N-carboxyanhydride structure, which readily undergoes ring-opening polymerization when activated, forming peptide bonds with remarkable control over stereochemistry. This means that the 'handedness' (chirality) of the leucine residue is precisely maintained throughout the synthesis process, a factor that is critically important for the biological activity and efficacy of the resulting peptides and proteins.

For those looking to buy L-Leucine NCA, sourcing from a reputable manufacturer is crucial. The purity and enantiomeric excess of the NCA directly impact the success of the peptide synthesis, affecting yield, purity of the final product, and the avoidance of unwanted side reactions. Our company, a trusted manufacturer in China, ensures that our (S)-4-Isobutyloxazolidine-2,5-dione meets stringent quality standards, offering a purity level of 98% or higher. This dedication to quality means researchers can confidently purchase our product, knowing they are using a reliable material for their critical applications.

The applications of L-Leu-NCA extend beyond basic peptide synthesis. It is a cornerstone in the creation of more complex structures, including polypeptides used in advanced drug delivery systems, biocompatible materials for medical implants, and sophisticated biomaterials for tissue engineering. The ability to control the sequence and stereochemistry of amino acid incorporation allows for the design of materials with highly specific properties. For example, the synthesis of isotactic poly-L-leucine, a biodegradable polymer, relies on the consistent quality of the L-Leu-NCA monomer.

When considering the purchase of this vital intermediate, price is often a factor for procurement managers and research scientists. We strive to offer competitive pricing for our (S)-4-Isobutyloxazolidine-2,5-dione, ensuring that advanced chemical synthesis is accessible. Our streamlined production processes and efficient supply chain allow us to provide cost-effective solutions without compromising on quality. If you are a researcher or a procurement specialist seeking a reliable supplier for your peptide synthesis needs, we encourage you to contact us for a quote. We are prepared to discuss your specific requirements, including pack sizes and delivery schedules, to support your valuable work in pharmaceutical research and development.

In summary, L-Leucine NCA (CAS 3190-70-3) is more than just a chemical reagent; it is an enabler of innovation in peptide science and biomaterials. By choosing us as your supplier, you secure a high-quality, enantiomerically pure product from an experienced manufacturer, backed by a commitment to customer satisfaction. Explore the possibilities and elevate your research with our premium chiral intermediates.