Peptide synthesis is a cornerstone of modern pharmaceutical research and development, enabling the creation of complex therapeutic agents, diagnostics, and research tools. At the heart of efficient peptide synthesis lies the careful selection of protected amino acids, and N-alpha-FMOC-Nepsilon-BOC-L-Lysine (CAS 71989-26-9) stands out as a particularly vital component. As a leading manufacturer and supplier of high-quality pharmaceutical intermediates, we understand the intricacies involved in sourcing these critical materials.

Why N-alpha-FMOC-Nepsilon-BOC-L-Lysine?

Lysine, an essential amino acid, plays a crucial role in protein structure and function. In peptide synthesis, its side chain amino group (epsilon-amino) often requires protection to prevent unwanted reactions during chain elongation. N-alpha-FMOC-Nepsilon-BOC-L-Lysine achieves this through the use of two widely adopted orthogonal protecting groups: FMOC (9-fluorenylmethyloxycarbonyl) for the alpha-amino group and BOC (tert-butyloxycarbonyl) for the epsilon-amino group.

The FMOC group is base-labile, meaning it can be efficiently removed under mild basic conditions, typically using piperidine. This allows for the sequential addition of amino acids during solid-phase peptide synthesis (SPPS). The BOC group, on the other hand, is acid-labile, remaining stable during the FMOC deprotection steps. It is typically cleaved off in the final stage of peptide synthesis along with the cleavage of the peptide from the resin, usually with trifluoroacetic acid (TFA).

Benefits of Sourcing from a Reliable Manufacturer

When you look to buy N-alpha-FMOC-Nepsilon-BOC-L-Lysine, partnering with a reputable manufacturer like ourselves ensures you receive a product of exceptional quality. Our N-alpha-FMOC-Nepsilon-BOC-L-Lysine (CAS 71989-26-9) is characterized by:

  • High Purity: Typically exceeding 97%, this guarantees minimal side reactions and maximum yield in your synthesis.
  • Consistent Quality: We adhere to stringent quality control measures, ensuring batch-to-batch consistency, which is vital for reproducible research.
  • Optimized for SPPS: The protective group strategy is perfectly aligned with standard SPPS protocols, streamlining your workflow.
  • Competitive Pricing: As a direct manufacturer, we can offer competitive prices, making high-quality reagents more accessible for your projects.

Applications Beyond Basic Synthesis

Beyond its fundamental role in forming peptide bonds, N-alpha-FMOC-Nepsilon-BOC-L-Lysine serves as a platform for further modifications. The protected lysine residue can be functionalized to attach labels, tags, or even form conjugates with other molecules, expanding its utility in drug delivery systems and bioconjugation.

For researchers and procurement managers seeking to purchase N-alpha-FMOC-Nepsilon-BOC-L-Lysine, understanding the technical specifications and the supplier's reliability is paramount. We invite you to explore our offerings and experience the difference that quality and commitment make. Contact us today to request a quote or a sample and learn how we can support your advanced peptide synthesis requirements.