Mastering Peptide Synthesis with High-Purity (Fmoc-Cys-OtBu)2
Peptide synthesis is a cornerstone of modern pharmaceutical research and development, enabling the creation of life-saving drugs, therapeutic peptides, and advanced biomaterials. At the heart of efficient and reliable peptide synthesis lies the quality of the building blocks used. One such critical component is Bis(2-methyl-2-propanyl) N,N'-bis[(9H-fluoren-9-ylmethoxy)carbonyl]-L-cystinate, commonly referred to by its abbreviation (Fmoc-Cys-OtBu)2, and identified by CAS Number 139592-37-3.
For researchers and procurement managers looking to buy high-quality amino acid derivatives, understanding the specifications and benefits of (Fmoc-Cys-OtBu)2 is paramount. This protected form of L-cystine disulfide is a vital pharmaceutical intermediate, offering specific advantages in both solid-phase peptide synthesis (SPPS) and solution-phase methods. Its chemical structure, C44H48N2O8S2, with a molecular weight of 796.99 g/mol, provides the necessary stability and reactivity for complex peptide chain elongations.
The purity of any chemical intermediate directly impacts the success of the synthesis process. When sourcing (Fmoc-Cys-OtBu)2, a minimum purity of ≥98% is generally recommended to ensure minimal side reactions and to achieve the highest possible yield of the target peptide. A reputable manufacturer and supplier in China can guarantee this level of purity, offering consistency that is crucial for reproducible research and scalable production. The ability to purchase this essential reagent reliably from a trusted supplier streamlines laboratory operations and accelerates R&D timelines.
The applications of (Fmoc-Cys-OtBu)2 extend across various domains within the pharmaceutical industry. It is instrumental in the synthesis of therapeutic peptides for conditions ranging from metabolic disorders to cancer. Its use as a building block in medicinal chemistry facilitates the development of novel drug candidates by allowing for precise control over peptide sequences and modifications. Researchers often seek out this specific derivative for its unique disulfide bond formation capabilities, which are important for the structure and function of many biologically active peptides.
When considering where to purchase (Fmoc-Cys-OtBu)2, it is beneficial to partner with a supplier that not only provides the chemical itself but also offers comprehensive support. This includes clear product documentation, such as Certificates of Analysis (COA) detailing purity and quality, and efficient logistics for timely delivery. For any organization aiming to excel in peptide-based drug development, securing a consistent and high-quality supply of (Fmoc-Cys-OtBu)2 from a leading China manufacturer is a strategic advantage. This ensures that your R&D efforts are built on a foundation of reliable, high-performance chemical intermediates.
Perspectives & Insights
Future Origin 2025
“The ability to purchase this essential reagent reliably from a trusted supplier streamlines laboratory operations and accelerates R&D timelines.”
Core Analyst 01
“The applications of (Fmoc-Cys-OtBu)2 extend across various domains within the pharmaceutical industry.”
Silicon Seeker One
“It is instrumental in the synthesis of therapeutic peptides for conditions ranging from metabolic disorders to cancer.”