In the complex world of pharmaceutical manufacturing, the selection of high-quality intermediates is paramount to the success of drug synthesis. Among these vital compounds, 7-(4-Chlorobutoxy)-2(1H)-quinolinone, identified by its CAS number 913613-82-8, stands out as a crucial building block. This article delves into the significance of this chemical entity, its applications, and why partnering with a reputable manufacturer for its procurement is essential for pharmaceutical companies. We'll explore how sourcing this intermediate can directly impact the efficiency and success of your drug development programs, particularly for treatments targeting central nervous system (CNS) disorders.

Understanding 7-(4-Chlorobutoxy)-2(1H)-quinolinone: A Pharmaceutical Cornerstone

7-(4-Chlorobutoxy)-2(1H)-quinolinone is a chemical compound with the molecular formula C13H14ClNO2 and a molecular weight of approximately 251.71 g/mol. Typically appearing as a white powder, this compound possesses specific chemical properties that make it an ideal intermediate for complex organic synthesis. Its primary importance lies in its role in the production of pharmaceutical active ingredients (APIs). For instance, it is a well-known intermediate in the synthesis of Brexpiprazole, a medication used to treat conditions such as schizophrenia and major depressive disorder. The demand for high-purity intermediates like this one is consistently high as the pharmaceutical industry strives for more effective and targeted therapies.

Key Applications and Benefits in Drug Development

The strategic importance of 7-(4-Chlorobutoxy)-2(1H)-quinolinone cannot be overstated. Its structure allows for further functionalization, making it a versatile precursor for a range of quinoline-based pharmaceuticals. Beyond Brexpiprazole, researchers are exploring its utility in developing other novel agents for CNS disorders. By ensuring the availability of this intermediate, pharmaceutical R&D teams can accelerate their discovery pipelines and streamline the manufacturing process. Procurement managers looking to buy this compound should prioritize suppliers who can guarantee consistent quality, typically above 98% purity, confirmed via analytical methods like HPLC. This focus on purity is critical to avoid unwanted side reactions or impurities in the final API, directly impacting drug safety and efficacy.

Sourcing from Trusted Manufacturers in China

China has emerged as a global hub for chemical manufacturing, offering a vast array of pharmaceutical intermediates. For companies seeking to purchase 7-(4-Chlorobutoxy)-2(1H)-quinolinone, partnering with a reliable Chinese manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. can provide significant advantages. These manufacturers often offer competitive pricing, robust production capacities, and comprehensive quality control systems. When evaluating suppliers, it is advisable to inquire about their production capabilities, quality certifications, and the availability of detailed technical documentation, such as Certificates of Analysis (CoA). Understanding the production process, from synthesis to purification, ensures that the intermediate meets the stringent requirements of pharmaceutical applications. This proactive approach to supplier selection is key to establishing a stable and dependable supply chain.

Ensuring Quality and Safety in Handling

Like many fine chemicals, 7-(4-Chlorobutoxy)-2(1H)-quinolinone requires careful handling and storage to maintain its integrity. It is generally classified with warning labels indicating potential hazards, such as skin and eye irritation, and harm if inhaled or swallowed. Following recommended safety protocols, including the use of personal protective equipment (PPE) and proper ventilation, is crucial for laboratory and plant personnel. Storage in an inert atmosphere at room temperature is often recommended to preserve its stability. By adhering to these guidelines, manufacturers and end-users can ensure the safe and effective use of this valuable pharmaceutical intermediate.

In conclusion, 7-(4-Chlorobutoxy)-2(1H)-quinolinone is an indispensable component in the pharmaceutical industry, particularly for the synthesis of advanced CNS therapies. Its role in Brexpiprazole production highlights its market relevance. For companies looking to secure a high-quality supply, understanding the product's characteristics and choosing a reputable Chinese manufacturer are critical steps. By focusing on purity, reliability, and safety, pharmaceutical professionals can effectively leverage this key intermediate to drive innovation and bring life-changing medications to market.