The journey from raw chemical to a life-changing medication is complex, relying heavily on the quality and availability of key pharmaceutical intermediates. Among these vital components, N-(2-cyano-4-oxochromen-8-yl)-4-(4-phenylbutoxy)benzamide stands out as an indispensable building block in the synthesis of Pranlukast. Pranlukast, a potent leukotriene receptor antagonist, has been a cornerstone in the management of asthma and allergic conditions, offering relief to millions worldwide. Understanding the synthesis of this crucial intermediate is paramount for pharmaceutical manufacturers and researchers aiming to ensure a stable and high-quality supply chain.

N-(2-cyano-4-oxochromen-8-yl)-4-(4-phenylbutoxy)benzamide, identified by its CAS number 136450-11-8, is characterized by its white to off-white powder appearance and remarkable purity, often exceeding 99%. This high degree of purity is not merely a specification but a critical requirement for pharmaceutical applications, ensuring that subsequent reactions proceed efficiently and the final API meets stringent regulatory standards. The compound's physical properties, such as its density of 1.3 g/cm³ and a high flash point of 301.0±30.1°C, contribute to its stability during handling and processing, making it a reliable choice for complex chemical synthesis.

The primary application of this benzamide derivative lies in its direct role as an intermediate in the production of Pranlukast. The intricate molecular structure of N-(2-cyano-4-oxochromen-8-yl)-4-(4-phenylbutoxy)benzamide provides the necessary reactive sites and structural framework that are meticulously transformed through various chemical reactions to yield Pranlukast. For companies seeking to buy Pranlukast intermediate, the focus must be on sourcing from reputable manufacturers who can guarantee consistency and adherence to pharmacopoeial standards. Many pharmaceutical intermediate manufacturers in China have developed sophisticated production processes, including continuous flow techniques, to achieve the required purity and scalability for this compound.

Beyond its established role, the structural complexity of N-(2-cyano-4-oxochromen-8-yl)-4-(4-phenylbutoxy)benzamide also presents opportunities for further research in medicinal chemistry. Its unique combination of a benzamide core and a chromene moiety makes it a promising candidate for derivatization, potentially leading to the discovery of novel therapeutic agents with anti-inflammatory, analgesic, or even anticancer properties. The consistent availability of high-purity intermediates like this is a catalyst for innovation in the field. When researching or scaling up production, understanding the chemical synthesis of asthma medication involves meticulous attention to the quality of each precursor. Sourcing from a reliable N-(2-cyano-4-oxochromen-8-yl)-4-(4-phenylbutoxy)benzamide supplier is a critical step in ensuring the success and efficiency of your pharmaceutical development projects.

In summary, N-(2-cyano-4-oxochromen-8-yl)-4-(4-phenylbutoxy)benzamide is more than just a chemical compound; it is a critical enabler in the production of essential medicines. Its high purity, stability, and specific chemical properties underscore its importance in the pharmaceutical industry. For those involved in the synthesis of Pranlukast or exploring new frontiers in respiratory health, securing a dependable supply of this key intermediate is fundamental.