The Suzuki-Miyaura coupling reaction has revolutionized organic synthesis, offering a robust and versatile method for forging carbon-carbon bonds. At the heart of many successful Suzuki couplings lies a diverse array of boronic acids, each with unique properties and applications. Among these, 3-Carboxyphenylboronic Acid (CAS: 25487-66-5) is a particularly valuable reagent, widely sought after by researchers and manufacturers in the pharmaceutical and fine chemical sectors. As a premier manufacturer and supplier based in China, NINGBO INNO PHARMCHEM CO.,LTD. is at the forefront of providing this essential chemical intermediate.

The Chemistry of 3-Carboxyphenylboronic Acid in Suzuki Coupling

3-Carboxyphenylboronic Acid, appearing as an off-white crystalline powder with a purity of ≥98.0%, is an arylboronic acid that offers excellent reactivity in Suzuki coupling. The presence of the carboxylic acid group on the phenyl ring provides an additional functional handle for further chemical modifications or can influence the electronic properties of the molecule, leading to optimized reaction outcomes. Its application extends beyond mere catalysis, making it a critical component in the synthesis of pharmaceuticals such as Eltrombopag and Lumacaftor, where precise molecular construction is non-negotiable.

When sourcing this vital compound, choosing a reliable supplier is paramount. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. in China offer the advantage of economies of scale, advanced quality control, and competitive pricing. This allows businesses to buy 3-Carboxyphenylboronic Acid efficiently, ensuring consistent material quality for their complex synthetic processes. Understanding the pricing and availability from a trusted manufacturer can significantly streamline procurement and R&D efforts.

Applications Beyond Pharmaceuticals

While its role in pharmaceutical synthesis is prominent, 3-Carboxyphenylboronic Acid also finds utility in the development of advanced materials and agrochemicals, owing to the versatility of the Suzuki coupling reaction. Its ability to participate in selective cross-coupling reactions makes it an attractive starting material for creating new organic molecules with tailored properties. For formulators and research scientists, the ability to source this intermediate reliably and cost-effectively from a dedicated supplier like NINGBO INNO PHARMCHEM CO.,LTD. is a significant advantage.

We encourage procurement managers and R&D scientists to inquire about purchasing 3-Carboxyphenylboronic Acid. By partnering with NINGBO INNO PHARMCHEM CO.,LTD., you ensure access to a high-quality chemical intermediate from a trusted manufacturer in China, supporting your innovative projects and production needs with efficiency and reliability.