The Suzuki-Miyaura cross-coupling reaction is a cornerstone of modern organic synthesis, renowned for its versatility in forming carbon-carbon bonds. At the heart of many successful Suzuki-Miyaura couplings lies the quality of the boronic acid used. For researchers and procurement managers in the pharmaceutical and fine chemical industries, sourcing a reliable and high-purity boronic acid is paramount. This is where compounds like 3,5-Difluorophenylboronic acid (CAS: 156545-07-2) from NINGBO INNO PHARMCHEM CO.,LTD. shine.

Why Choose High-Purity 3,5-Difluorophenylboronic Acid?

3,5-Difluorophenylboronic acid, a key fluorine-containing organic intermediate, offers unique advantages. Its specific molecular structure, featuring fluorine atoms at the meta positions of the phenyl ring, can influence reactivity, lipophilicity, and the biological activity of the final synthesized compounds. When you need to buy this essential building block, opting for a product with guaranteed purity, such as the 99% offered by NINGBO INNO PHARMCHEM CO.,LTD., ensures:

  • Reproducible Results: Impurities can lead to side reactions and lower yields, compromising the integrity of your research or production. High purity minimizes these risks.
  • Enhanced Reactivity: A purer boronic acid typically exhibits more consistent and vigorous participation in catalytic cycles, leading to faster reaction times and higher conversion rates.
  • Cost-Effectiveness: While the upfront cost might seem higher, the efficiency gains and reduction in waste from using a high-purity intermediate often translate to lower overall production costs.

The Role in Suzuki-Miyaura Coupling

The Suzuki-Miyaura reaction involves the palladium-catalyzed cross-coupling of an organoboron compound (like a boronic acid) with an organohalide. 3,5-Difluorophenylboronic acid is an excellent coupling partner for various aryl and vinyl halides. Its application is widespread in:

  • Pharmaceutical Synthesis: Developing new drug candidates targeting various diseases often requires complex molecular architectures. This boronic acid serves as a critical building block for introducing fluorinated phenyl moieties, which can enhance drug efficacy and metabolic stability. Researchers often search for 'high purity 3,5-difluorophenylboronic acid supplier' or 'pharmaceutical intermediate price' when sourcing for these applications.
  • Materials Science: The ability to precisely incorporate fluorinated aromatic rings is valuable in creating advanced materials with tailored electronic or optical properties.

Sourcing from NINGBO INNO PHARMCHEM CO.,LTD.

As a leading manufacturer and supplier of organic intermediates, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing top-tier 3,5-Difluorophenylboronic acid. We understand the critical needs of our B2B clients. Whether you are a research scientist looking to buy small quantities for a pilot study or a procurement manager needing bulk supply for industrial production, we offer competitive pricing and reliable delivery. Contact us to inquire about the price for 3,5-Difluorophenylboronic acid and to explore how our commitment to quality can benefit your next synthesis project.