In the intricate world of pharmaceutical development and fine chemical synthesis, achieving precise stereochemistry is paramount. The biological activity of many drugs is intricately linked to their chirality, making enantioselective synthesis a cornerstone of modern organic chemistry. Among the most powerful tools available for this purpose are chiral oxazaborolidine catalysts. These compounds, often referred to as CBS catalysts (after their discoverers Corey, Bakshi, and Shibata), play a pivotal role in directing the stereochemical outcome of reactions.

One such critical catalyst is (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole, identified by CAS number 112022-81-8. This specific enantiomer is renowned for its efficacy in the asymmetric reduction of prochiral ketones to yield chiral secondary alcohols. The mechanism involves the coordination of the borane reductant with the oxazaborolidine catalyst, creating a chiral environment that guides the hydride transfer to one face of the carbonyl group more readily than the other. This results in a highly enantioselective process, crucial for producing chiral intermediates that are building blocks for many pharmaceuticals.

For R&D scientists and procurement managers in the pharmaceutical and agrochemical sectors, sourcing high-quality chiral catalysts is a constant challenge. The need for consistent purity, reliable supply, and competitive pricing drives the search for dependable manufacturers. As a leading chemical manufacturer and supplier in China, we understand these demands. We specialize in providing advanced chemical intermediates and catalysts, including (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole, to meet the rigorous standards of the global market.

The applications of this oxazaborolidine catalyst extend beyond simple ketone reduction. It is instrumental in the synthesis of chiral α-hydroxy acids, chiral α-amino acids, and other complex stereodefined molecules. These compounds are often precursors to potent drugs and biologically active molecules. By employing our (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole, researchers can confidently develop synthetic routes that yield the desired enantiomer with high fidelity. We encourage interested parties to inquire about bulk purchase options and competitive pricing from our dedicated sales team. Partner with a manufacturer committed to excellence in chiral synthesis.