Protein modification is a cornerstone of modern biochemical research and pharmaceutical development. Precisely altering the properties of proteins can lead to enhanced therapeutic efficacy, improved diagnostic sensitivity, and novel functional materials. Among the most effective tools for protein modification is the succinimidyl ester derivative of polyethylene glycol (PEG), and specifically, 3-(2-Methoxyethoxy)propanoic acid succinimidyl ester (MeO-EPr-NHS ester). This reagent, known for its amine reactivity and excellent solubility-enhancing properties, is a must-have for any laboratory focused on protein science.

MeO-EPr-NHS ester functions by reacting with the primary amine groups present on protein surfaces, most notably the epsilon-amino groups of lysine residues and the N-terminus of the polypeptide chain. This reaction results in the formation of a stable amide bond, covalently attaching the PEG moiety to the protein. When you buy MeO-EPr-NHS ester, you are acquiring a reagent that facilitates controlled PEGylation. The benefits of such modification are manifold: increased hydrodynamic radius, leading to longer circulation times in vivo; improved solubility, which is crucial for proteins that are otherwise poorly soluble; and protection against proteolytic degradation, enhancing protein stability.

As a leading CAS 1127247-34-0 manufacturer, our focus is on delivering MeO-EPr-NHS ester with superior quality. We ensure a purity level exceeding 98%, which is critical for achieving predictable and reproducible protein modification outcomes. High-purity reagents are essential when working with sensitive biological molecules, and our product meets these stringent requirements. We understand that cost-effectiveness is also a significant consideration for our clients, and we strive to offer a competitive price for MeO-EPr-NHS ester without compromising on quality.

The structure of MeO-EPr-NHS ester, featuring a short, flexible PEG chain with a methoxyethoxy modification, provides a unique balance of reactivity and solubility enhancement. This makes it particularly useful for applications such as developing protein-based therapeutics, diagnostic assays, and bioconjugates for imaging or targeted delivery. When you require a reliable amine reactive PEG linker for bioconjugation, MeO-EPr-NHS ester from our company stands out as an excellent choice.

Researchers seeking to buy high-purity PEGylation reagents can rely on our consistent supply and expertise. We are a dedicated supplier of MeO-EPr-NHS in China, committed to supporting the scientific community with essential chemical building blocks. Whether you are aiming to improve the pharmacokinetic profile of a therapeutic protein or developing a novel diagnostic tool, MeO-EPr-NHS ester is an invaluable asset.