In the intricate world of pharmaceutical research and development, the availability of precisely synthesized chemical intermediates is fundamental to progress. Mesitylacetonitrile (CAS 34688-71-6) has emerged as a significant compound, valued for its role in creating complex molecules, particularly those with therapeutic potential. This article explores the significance of Mesitylacetonitrile for pharmaceutical R&D and offers guidance on how to efficiently procure this vital chemical.

The Chemical Identity of Mesitylacetonitrile

Mesitylacetonitrile, identified by its CAS registry number 34688-71-6, is a nitrile compound with the chemical formula C11H13N. Its structure combines a reactive nitrile group with a mesityl moiety, making it a valuable synthon in organic chemistry. The compound is typically supplied as a solid, often described as white to off-white crystals. High purity, typically above 98%, is essential for its application in pharmaceutical research to ensure the integrity and reproducibility of experimental results. Manufacturers often provide detailed specifications, including its molecular weight (159.23 g/mol) and various synonyms such as (2,4,6-trimethylphenyl)acetonitrile.

Applications in Pharmaceutical Research and Synthesis

The utility of Mesitylacetonitrile in pharmaceutical research stems from its ability to serve as a key intermediate in the synthesis of biologically active compounds. It has been implicated in the development of novel therapeutic agents, including those investigated for their efficacy against viral infections like HIV, and compounds aimed at managing stress-related disorders. Its well-defined chemical structure and predictable reactivity allow researchers to build complex molecular frameworks with greater control. When scientists need to buy this chemical for their drug discovery programs, they look for suppliers who can guarantee consistent quality and reliable delivery.

Procurement Strategies for Mesitylacetonitrile

For R&D teams and procurement specialists, securing a consistent supply of Mesitylacetonitrile is critical. When searching for manufacturers or suppliers, it is important to consider factors such as purity specifications, availability in desired quantities (from research-scale grams to bulk production kilograms), and competitive pricing. Suppliers based in major chemical manufacturing hubs, such as China, often offer cost advantages. Requesting a Certificate of Analysis (CoA) for each batch is a standard practice to verify product quality and ensure it meets the rigorous demands of pharmaceutical research. Establishing a relationship with a trusted supplier ensures a reliable pipeline of this essential chemical intermediate for ongoing projects.

By understanding the role and sourcing requirements of Mesitylacetonitrile, pharmaceutical researchers can optimize their workflows and accelerate the discovery and development of new medicines.