Methyl 2,3-dichloropropionate (CAS 3674-09-7) is a specialized chemical intermediate that holds significant importance in various sectors, primarily within the pharmaceutical and fine chemical industries. Its unique chemical structure and properties make it an indispensable component in complex synthetic pathways. For chemical professionals, understanding the characteristics and sourcing of this compound is key to successful project execution.

Chemical Identity and Properties

Methyl 2,3-dichloropropionate, with the CAS number 3674-09-7, is characterized by its molecular formula C4H6Cl2O2. It is typically described as a clear, colorless to slightly yellow liquid. Its physical parameters, such as a density of 1.328 g/mL and a boiling point of 92°C at 50 mmHg, are critical for handling and reaction planning. The compound's flash point is 42°C, indicating a need for careful storage and handling procedures. Manufacturers usually guarantee a purity of at least 97%, ensuring its efficacy as a reliable intermediate for synthesis.

Synthesis Methods and Manufacturing

The production of Methyl 2,3-dichloropropionate typically involves the chlorination of methyl acrylate. This synthesis route often employs controlled conditions to maximize yield and purity. For example, reacting methyl acrylate with chlorine gas in the presence of a suitable solvent like dimethylformamide (DMF) and maintaining a specific temperature range is a common approach. The product is then purified through distillation. For businesses looking to buy Methyl 2,3-dichloropropionate, understanding the manufacturing process provides insight into the quality and consistency they can expect from a reputable manufacturer.

Applications in Pharmaceuticals and Beyond

The most prominent application of Methyl 2,3-dichloropropionate is its role as a pharmaceutical intermediate. It serves as a foundational building block in the synthesis of various Active Pharmaceutical Ingredients (APIs), contributing essential structural elements to drug molecules. Its utility extends to general organic synthesis, where it can be employed in reactions that create other valuable chemicals or intermediates. Researchers and industrial chemists seek out this compound for its versatility in building complex molecular structures. The ability to purchase Methyl 2,3-dichloropropionate from reliable sources ensures the continuity of these vital synthetic processes.

Global Sourcing and Supply Chain Management

The global supply of Methyl 2,3-dichloropropionate is supported by a network of manufacturers, with China being a significant contributor to the market. When sourcing this chemical, professionals must prioritize suppliers who offer high purity, competitive pricing, and dependable delivery. Evaluating potential suppliers involves scrutinizing their product specifications, quality control measures, and customer service. Obtaining quotes for the CAS 3674-09-7 price and understanding lead times are critical aspects of the procurement process. NINGBO INNO PHARMCHEM CO.,LTD. is a prominent example of a company dedicated to providing high-quality chemical intermediates, acting as a reliable link in the global chemical supply chain.

Conclusion

Methyl 2,3-dichloropropionate is an essential chemical intermediate with diverse applications, especially in the pharmaceutical industry. By focusing on detailed product knowledge, understanding synthesis routes, and engaging with reliable global suppliers, chemical professionals can effectively secure the materials needed for their critical projects, ensuring both quality and cost-efficiency.