Methyl (2R)-3-Hydroxy-2-Methylpropanoate, identified by its CAS number 72657-23-9, is a specialized chiral ester that has garnered significant attention in various industrial sectors, particularly pharmaceuticals and cosmetics. Its unique stereochemistry and chemical functionality make it a valuable raw material for complex synthesis and formulation. Understanding its key properties is essential for R&D scientists and procurement managers looking to buy or incorporate it into their processes.

The physical appearance of this compound is typically described as a clear, colorless liquid. Its molecular formula is C5H10O3, with a molecular weight of approximately 118.13 g/mol. A critical characteristic is its chirality, specifically the (2R) enantiomer. This stereochemical definition is vital for its function in stereoselective synthesis, where precise molecular architecture dictates biological activity or material performance. Suppliers often highlight its high purity, frequently rated at 98% or above, ensuring minimal interference from impurities in sensitive reactions or formulations. The optical rotation, often reported as [α]19/D 26° (c = 4 in methanol), further confirms its specific chiral nature.

The chemical properties of Methyl (2R)-3-Hydroxy-2-Methylpropanoate make it a versatile intermediate. The presence of a secondary alcohol group and a methyl ester group provides reactive sites for various chemical transformations, including esterification, oxidation, and nucleophilic substitution. This allows it to serve as a fundamental building block in multi-step syntheses. For example, it can be used in the preparation of complex molecules where the hydroxyl group needs to be functionalized or the ester needs to be hydrolyzed or transesterified.

Its applications are primarily concentrated in the synthesis of pharmaceuticals and cosmetic ingredients. In the pharmaceutical industry, it functions as a chiral synthon for producing enantiomerically pure active pharmaceutical ingredients (APIs). This precision is crucial for drug efficacy and safety, as different enantiomers can have vastly different pharmacological effects. For cosmetic formulators, this compound may be used in creating novel skincare actives or enhancing product feel and performance. Businesses seeking to purchase this chemical will find that reliable manufacturers and suppliers, often based in China, offer it with guaranteed specifications.

When considering the purchase of Methyl (2R)-3-Hydroxy-2-Methylpropanoate, potential buyers should always request detailed technical data sheets and ensure the supplier can provide batch-specific Certificates of Analysis. Understanding the shipping terms, minimum order quantities, and payment options is also part of a successful B2B transaction. For those looking to buy this chemical, engaging with experienced suppliers ensures access to a high-quality, precisely characterized ingredient essential for advanced industrial applications.