Methyl 3,5-diamino-6-chloropyrazine-2-carboxylate, identified by its CAS number 1458-01-1, is a chemical compound of significant interest across various scientific and industrial domains, particularly in organic synthesis, pharmaceutical research, and agrochemical development. Understanding its properties is crucial for researchers and procurement specialists seeking to leverage its potential.

Chemical Structure and Properties: This compound features a chloropyrazine core substituted with two amino groups and a methyl ester group. The pyrazine ring, a six-membered aromatic heterocycle with two nitrogen atoms, contributes to its unique electronic properties. The amino groups and the chlorine atom provide reactive sites that are essential for its function as a chemical intermediate. Its molecular formula is C6H7ClN4O2, and it has a molecular weight of approximately 202.60 g/mol. Typically, it presents as a white to yellow powder or crystals, with a melting point range of 211-215°C, indicating its solid state under standard conditions.

Key Applications: The primary utility of Methyl 3,5-diamino-6-chloropyrazine-2-carboxylate lies in its role as a synthesis intermediate. In the pharmaceutical industry, it is a valuable building block for the creation of various drug candidates, including those being investigated for antimicrobial and anticancer activities. Its functional groups allow for diverse derivatization, making it a versatile component in drug discovery pipelines. For example, it serves as a precursor for Amiloride related compounds, which are known for their diuretic properties.

In the agrochemical sector, this compound acts as an intermediate in the synthesis of herbicides and fungicides. Its incorporation into active ingredients can lead to more effective and targeted crop protection solutions. The ability to modify its structure allows for the fine-tuning of biological activity, ensuring efficacy against pests and diseases while maintaining plant health and safety.

For scientists involved in general organic synthesis, Methyl 3,5-diamino-6-chloropyrazine-2-carboxylate offers a reactive platform for exploring new chemical transformations and creating novel molecular architectures. Its availability from chemical suppliers in China, often with high purity levels (e.g., 97% min.), makes it accessible for both research and industrial applications. When purchasing this chemical, buyers should consult the manufacturer's specifications and request relevant documentation like CoAs to ensure quality and suitability for their intended use.

In essence, Methyl 3,5-diamino-6-chloropyrazine-2-carboxylate is a critical fine chemical intermediate, underpinning advancements in both healthcare and agriculture. Its diverse applications underscore the importance of a reliable chemical supply chain for researchers and manufacturers worldwide.