Understanding Methyl 4-acetamido-2-hydroxybenzoate: Properties, Synthesis, and Sourcing in China
Methyl 4-acetamido-2-hydroxybenzoate, a compound identified by CAS number 4093-28-1, plays a pivotal role in the pharmaceutical industry, primarily as an intermediate in the synthesis of Mosapride. Mosapride is a gastroprokinetic agent known for its efficacy in treating various gastrointestinal motility disorders. The importance of this intermediate necessitates a thorough understanding of its properties, synthesis, and reliable sourcing channels.
The chemical synthesis of Methyl 4-acetamido-2-hydroxybenzoate typically begins with methyl 4-aminosalicylic acid, which undergoes acetylation. This reaction, often carried out using acetyl chloride in a suitable solvent like ethyl acetate and in the presence of a base such as sodium bicarbonate, proceeds efficiently to yield the desired product. Manufacturers in China have established robust and scalable synthesis protocols for this compound, consistently delivering material with high purity, often exceeding 95%. This focus on quality is crucial for its application in pharmaceutical manufacturing, where strict regulatory standards must be met.
As a key pharmaceutical intermediate, Methyl 4-acetamido-2-hydroxybenzoate is sought after by drug manufacturers globally. Companies looking to buy methyl 4-acetamido-2-hydroxybenzoate often turn to Chinese suppliers due to their competitive pricing, large production capacities, and well-developed export logistics. These suppliers provide comprehensive product information, including Certificates of Analysis (CoA), ensuring traceability and quality assurance for each batch. The accessibility through online platforms further simplifies the procurement process for researchers and manufacturers alike.
The reliability and cost-effectiveness offered by Chinese manufacturers in the production of Methyl 4-acetamido-2-hydroxybenzoate are significant advantages for the pharmaceutical sector. By ensuring a steady supply of this essential intermediate, they contribute to the efficient and affordable production of vital medications, ultimately benefiting patients worldwide. For any entity involved in the synthesis of Mosapride or related chemical research, understanding these sourcing dynamics is key to successful project execution.
Perspectives & Insights
Data Seeker X
“The chemical synthesis of Methyl 4-acetamido-2-hydroxybenzoate typically begins with methyl 4-aminosalicylic acid, which undergoes acetylation.”
Chem Reader AI
“This reaction, often carried out using acetyl chloride in a suitable solvent like ethyl acetate and in the presence of a base such as sodium bicarbonate, proceeds efficiently to yield the desired product.”
Agile Vision 2025
“Manufacturers in China have established robust and scalable synthesis protocols for this compound, consistently delivering material with high purity, often exceeding 95%.”