Methyl 4'-(bromomethyl)biphenyl-2-carboxylate, identified by its CAS number 114772-38-2, is a sophisticated organic compound that plays a pivotal role in the synthesis of complex molecules, most notably the pharmaceutical agent Telmisartan. As a high-value intermediate, understanding its chemical and physical properties is essential for researchers and manufacturers aiming to optimize their synthetic pathways. This article delves into the key attributes of this compound and its significant applications.

Chemically, Methyl 4'-(bromomethyl)biphenyl-2-carboxylate has the molecular formula C15H13BrO2 and a molecular weight of approximately 305.17 g/mol. Its structure features a biphenyl core, which provides a rigid aromatic framework. Attached to this core are a methyl ester group (-COOCH3) and a bromomethyl group (-CH2Br). The bromomethyl group is particularly reactive, serving as an excellent electrophile for various organic transformations, such as alkylation reactions. This reactivity makes it a valuable synthon in organic chemistry.

Physically, this compound is typically described as a white to light yellow powder. Its melting point is around 56 °C, indicating it is a solid at room temperature. Other reported properties include a density of approximately 1.374 g/cm³. These physical characteristics are important for handling, storage, and formulation considerations, especially when working with the compound as a raw material from a manufacturer.

The primary application for Methyl 4'-(bromomethyl)biphenyl-2-carboxylate is as a key intermediate in the synthesis of Telmisartan. Telmisartan is a potent angiotensin II receptor blocker (ARB) used to treat hypertension and reduce cardiovascular risk. The biphenyl structure of the intermediate is critical for building the core of the Telmisartan molecule, and the bromomethyl group facilitates further functionalization necessary for achieving the final drug's therapeutic efficacy.

Beyond its role in Telmisartan synthesis, this compound can also serve as a building block in other areas of organic synthesis, including the development of novel pharmaceuticals, agrochemicals, or advanced materials. Researchers seeking this intermediate for their R&D projects can rely on dedicated suppliers to provide high-purity material. When considering to purchase Methyl 4'-(bromomethyl)biphenyl-2-carboxylate, obtaining it from a reputable manufacturer ensures the desired purity and consistent quality, which is crucial for reliable experimental results and scaled-up production.

For those interested in the price of cas 114772-38-2, market rates can vary based on purity, quantity, and supplier. Engaging with established chemical companies that specialize in fine chemicals and pharmaceutical intermediates, particularly those operating as a supplier in China, can provide competitive options. We are dedicated to supplying this vital intermediate to meet your research and manufacturing needs.

In conclusion, Methyl 4'-(bromomethyl)biphenyl-2-carboxylate is a chemically versatile and physically well-defined compound. Its established role in Telmisartan synthesis and its potential in broader organic chemistry applications make it a sought-after intermediate. We are a trusted source for this compound, ready to fulfill your requirements for high-quality material.