In the intricate world of pharmaceutical manufacturing, the quality and availability of raw materials and intermediates are foundational to producing safe and effective drugs. Methyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide, identified by its CAS number 35511-14-9, stands out as a critical pharmaceutical intermediate. Its primary application lies in the synthesis of Meloxicam, a widely prescribed non-steroidal anti-inflammatory drug (NSAID) used to treat conditions like arthritis. For pharmaceutical companies seeking to purchase this compound, understanding its role and how to source it reliably is paramount.

The Chemical's Role in Drug Synthesis

Methyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide serves as a vital precursor in the multi-step synthesis of Meloxicam. Its specific chemical structure provides the necessary reactive sites and backbone for the subsequent formation of the final active pharmaceutical ingredient (API). The purity and consistency of this intermediate directly impact the efficiency of the synthesis process and, more importantly, the purity profile of the final Meloxicam product. Therefore, sourcing from a reputable manufacturer that adheres to stringent quality control is essential.

Specifications and Sourcing from China

Typically described as an off-white to brown powder, Methyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide usually boasts an assay of ≥98.0%. This level of purity ensures that manufacturers can proceed with confidence in their synthetic pathways. When looking to source this compound, particularly from a supplier in China, factors like production capacity, quality certifications, and regulatory compliance should be carefully evaluated. Many global pharmaceutical firms rely on Chinese chemical manufacturers for cost-effectiveness and large-scale production capabilities. Engaging with a well-established manufacturer ensures that you can secure the required quantities at competitive prices.

Procurement Tips for Buyers

For procurement managers and R&D scientists, the process of acquiring this intermediate involves more than just finding the lowest price. It's about building a secure supply chain. Requesting detailed technical data sheets, understanding the packaging options (e.g., 25 kg/drum), and discussing delivery logistics are crucial steps before placing an order to buy. Furthermore, for significant purchases, negotiating supply agreements with reliable suppliers can offer greater stability and predictable costs. For those actively searching for this compound, using terms like 'CAS 35511-14-9 for sale' or 'Meloxicam intermediate manufacturer' will help pinpoint relevant sources.

In summary, Methyl 4-Hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide is an indispensable component in the pharmaceutical industry. Its quality and availability are directly linked to the successful production of Meloxicam. By prioritizing purity, working with reputable manufacturers and suppliers in China, and implementing sound procurement strategies, companies can ensure a robust supply of this critical intermediate.