Methyl 4-methoxysalicylate, identified by CAS number 5446-02-6, is a versatile organic compound that finds significant utility across various scientific disciplines, particularly in pharmaceutical synthesis and organic chemistry research. Understanding its properties and available supplier options is crucial for researchers and procurement professionals seeking this valuable intermediate. This article delves into the chemical characteristics, applications, and procurement considerations for Methyl 4-methoxysalicylate.

Chemically, Methyl 4-methoxysalicylate is an ester derivative of salicylic acid, featuring a methoxy group at the para position. Its molecular formula is C9H10O4, with a molecular weight of approximately 182.17 g/mol. Typically presented as a white to light yellow crystalline powder, it possesses a melting point in the range of 50-53 °C, indicating its solid state at room temperature. Its solubility profile often includes good solubility in organic solvents like acetone and chloroform, while being sparingly soluble or insoluble in water, which are important factors to consider during reaction planning and work-up procedures.

The applications of Methyl 4-methoxysalicylate are diverse and impactful. Primarily, it serves as a key organic building block. Researchers utilize it for the synthesis of complex natural products, notably the bioactive compounds (+)-coriandrone A and B. Furthermore, its role in preparing Dimethoxybenzofuran derivatives that act as potent and selective inhibitors of CYP2A6 enzymes underscores its importance in medicinal chemistry and the development of targeted therapeutics. For professionals in chemical synthesis, obtaining this compound from a reliable manufacturer is essential for reproducible results.

When it comes to purchasing Methyl 4-methoxysalicylate, B2B buyers often look for suppliers who can guarantee high purity, competitive pricing, and consistent availability. The global chemical market offers numerous options, with many suppliers specializing in pharmaceutical intermediates and fine chemicals. Companies based in China are frequently recognized for their manufacturing capabilities and cost-effectiveness. When evaluating suppliers, it's advisable to look for those who clearly state the product's purity (e.g., 98% min) and provide comprehensive technical data, such as CAS number, molecular formula, and physical properties.

The process of finding a suitable supplier usually involves online research, requesting quotes, and potentially ordering samples for verification. Websites dedicated to chemical sourcing and supplier directories can be invaluable resources. Engaging directly with manufacturers or their authorized distributors allows for direct communication regarding product specifications, minimum order quantities, and shipping logistics. For those involved in ongoing research or large-scale production, establishing a stable supply relationship with a reputable provider is a strategic advantage.

In conclusion, Methyl 4-methoxysalicylate (CAS 5446-02-6) is an indispensable intermediate in chemical synthesis, offering significant potential in pharmaceutical research and beyond. By understanding its properties and strategically identifying and vetting suppliers, procurement specialists can ensure the acquisition of high-quality material necessary for advancing scientific innovation and product development.