The synthesis of high-value compounds often hinges on the availability of precise chemical intermediates. Methyl L-Histidinate Dihydrochloride (CAS: 7389-87-9) stands out as a pivotal precursor, particularly for the production of L-(+)-ergothioneine, a potent antioxidant increasingly recognized for its benefits in health and wellness products. This article explores the significance of this intermediate and guides professionals on how to source it effectively.

The Role of Methyl L-Histidinate Dihydrochloride in Synthesis

Methyl L-Histidinate Dihydrochloride is a white, crystalline powder that serves as a fundamental building block for L-(+)-ergothioneine. This conversion process requires a high-purity starting material to ensure the final ergothioneine product is of the desired quality and free from unwanted byproducts. For researchers and manufacturers aiming to buy this compound, understanding its chemical properties and purity levels (typically ≥97%) is crucial for successful synthesis.

Sourcing for Ergothioneine Production

The growing market for ergothioneine, driven by its antioxidant and photoprotective properties, necessitates a reliable and scalable supply of its key intermediate. When selecting a supplier for Methyl L-Histidinate Dihydrochloride, consider these vital aspects:

  • Manufacturer Reputation: Partner with established manufacturers who specialize in amino acid derivatives and pharmaceutical intermediates. A strong reputation often indicates stringent quality control and reliable production.
  • Product Specification: Ensure the intermediate meets the required purity standards (e.g., 97% or higher) and that the CAS number 7389-87-9 is accurate. Requesting a Certificate of Analysis (CoA) is essential for verification.
  • Competitive Pricing: Obtain quotes from multiple sources to ensure competitive pricing. Factors like order volume and packaging can influence cost.
  • Supply Chain Reliability: A consistent supply is critical for production planning. Choose suppliers with a proven ability to deliver on time and in the required quantities.
  • Technical Expertise: Engage with suppliers who can provide technical support regarding the product's use in synthesis.

The Advantage of Sourcing from China

China has a vast chemical manufacturing industry, making it a prime location for sourcing intermediates like Methyl L-Histidinate Dihydrochloride. Many Chinese manufacturers offer high-quality products at competitive prices. However, it is imperative to conduct thorough due diligence to confirm their quality standards and reliability as a manufacturer.

Conclusion

Methyl L-Histidinate Dihydrochloride (CAS: 7389-87-9) is a critical intermediate for the production of L-(+)-ergothioneine. By strategically sourcing this compound from reputable manufacturers and suppliers, businesses can ensure the quality and efficiency of their synthesis processes. Prioritizing purity, reliability, and competitive pricing will enable you to meet the growing demand for ergothioneine and other derivative products.