For manufacturers specializing in fine chemicals and pharmaceutical intermediates, understanding the properties and applications of key reagents is fundamental. Methyl Malonyl Chloride (CAS: 37517-81-0) stands out as a valuable intermediate, widely utilized in complex organic synthesis. Its unique chemical structure and reactivity make it indispensable for various manufacturing processes, particularly in the pharmaceutical sector.

Methyl Malonyl Chloride is characterized by its bifunctional nature, containing both an ester group and a reactive acid chloride. This combination allows it to act as an efficient acylating agent and a precursor for malonic ester derivatives. Chemically, it typically presents as a clear to yellow liquid with a density of approximately 1.273 g/mL and a boiling point around 57-59 °C at 12 mmHg. Its hygroscopic nature means it reacts with water, necessitating careful handling and storage, preferably at 2-8°C.

The primary application for Methyl Malonyl Chloride is as a pharmaceutical intermediate, notably in the synthesis of anti-cancer drugs. Its incorporation into synthetic routes allows for the precise construction of complex molecular frameworks required for therapeutic efficacy. Beyond pharmaceuticals, it also finds use in the broader field of organic synthesis as a versatile building block for creating various fine chemicals.

Manufacturers seeking to buy Methyl Malonyl Chloride often turn to specialized chemical producers. China has a significant presence in the global supply of such intermediates, offering high-purity grades (often 97% or above) at competitive prices. When sourcing, it is essential to partner with manufacturers who can demonstrate consistent quality, reliable production capacity, and adherence to safety standards. This ensures that your manufacturing processes are not hindered by raw material variability.

As a leading manufacturer and supplier ourselves, we are dedicated to providing Methyl Malonyl Chloride that meets stringent quality requirements. We understand the critical role this intermediate plays in your production cycles and are committed to ensuring a stable and dependable supply. We encourage potential buyers to reach out for detailed product specifications, pricing, and to discuss your specific bulk purchase needs. Leveraging our expertise ensures you receive a quality product to drive your manufacturing success.