Methyl Oxalyl Chloride, identified by its CAS number 5781-53-3, stands as a pivotal organic intermediate within the chemical and pharmaceutical industries. Its unique reactivity and structure make it an indispensable building block for a wide array of complex organic molecules. For researchers and procurement managers seeking high-quality synthetic reagents, understanding the applications and sourcing options for this compound is paramount.

The primary utility of Methyl Oxalyl Chloride lies in its role as a versatile synthetic reagent. It is particularly valued for its ability to participate in regioselective synthesis of fused coumarins, a class of compounds with significant pharmaceutical and photophysical properties. Furthermore, it plays a crucial role in cyclization reactions to form substituted isoxazoles and other heterocycles, which are fundamental structural motifs in many active pharmaceutical ingredients (APIs). Its application extends to intramolecular Wittig reactions and iron-mediated cleavage of C-C bonds, enabling sophisticated molecular engineering.

When considering the purchase of Methyl Oxalyl Chloride, purity is a critical factor. Many suppliers offer grades with varying purity levels, but for demanding applications such as pharmaceutical intermediate synthesis, a high purity assay, often exceeding 99.5%, is essential. This ensures predictable reaction outcomes and minimizes the risk of unwanted byproducts. For businesses looking to buy Methyl Oxalyl Chloride, identifying a reputable manufacturer and supplier, especially one based in China known for its robust chemical production capabilities, can offer significant advantages in terms of both cost-effectiveness and reliable supply.

Procuring this chemical involves understanding its specifications, including its appearance as a colorless transparent liquid, its molecular formula (C3H3ClO3), and its molecular weight (122.51). Moisture sensitivity is another key characteristic that necessitates careful handling and storage. Procurement managers often look for suppliers who can provide comprehensive technical data sheets (TDS) and safety data sheets (SDS) to ensure safe and effective utilization.

For companies in the pharmaceutical sector or specialized chemical manufacturing, securing a consistent and competitive price for Methyl Oxalyl Chloride is vital for project viability. Engaging directly with manufacturers or their authorized distributors can lead to better pricing and supply chain transparency. Exploring options for online purchase or requesting a detailed quote from trusted suppliers in China can streamline the procurement process. As the demand for innovative therapeutics grows, the importance of reliable access to key intermediates like Methyl Oxalyl Chloride will only increase, underscoring the need for strategic partnerships with experienced chemical manufacturers.