In the realm of pharmaceutical development, the selection of Active Pharmaceutical Ingredients (APIs) is a meticulous process, where purity, efficacy, and consistency are paramount. Miconazole (CAS 22916-47-8) stands out as a crucial imidazole antifungal agent, widely incorporated into topical, oral, and vaginal formulations for treating a broad spectrum of fungal infections. This article delves into why Miconazole is indispensable for pharmaceutical applications and how to ensure you are sourcing the highest quality product.

The Pharmaceutical Significance of Miconazole

Miconazole's therapeutic value stems from its potent antifungal activity. It operates by disrupting the fungal cell membrane's integrity through the inhibition of ergosterol synthesis, a key component for fungal cell wall stability. This mechanism makes it effective against dermatophytes, yeasts (like Candida albicans), and other pathogenic fungi. For pharmaceutical formulators, this means a reliable ingredient to combat common fungal ailments such as athlete's foot, ringworm, jock itch, and candidiasis.

Key Considerations for Sourcing Pharmaceutical-Grade Miconazole

When seeking to buy Miconazole for pharmaceutical use, several critical factors must be addressed:

  • Regulatory Compliance: Pharmaceutical-grade Miconazole must meet stringent pharmacopoeial standards, such as USP, EP, or BP. A reputable manufacturer will provide comprehensive documentation, including Certificates of Analysis (CoA) that confirm compliance with these standards. This ensures that the API meets all necessary quality and safety benchmarks for human use.
  • Purity and Impurity Profiling: The purity of Miconazole is non-negotiable. While the compound is generally supplied at high purity (e.g., ≥98%), understanding the impurity profile is also vital. Trace impurities can impact the safety and efficacy of the final drug product. Partnering with a manufacturer that implements rigorous quality control throughout its synthesis process is key.
  • Manufacturing Consistency: Pharmaceutical companies require a stable and predictable supply chain. Sourcing Miconazole from manufacturers with established production processes and a track record of consistency is essential for uninterrupted drug manufacturing. Look for suppliers who can demonstrate robust batch-to-batch consistency.
  • Supplier Reputation: Research the supplier's reputation and experience in the pharmaceutical chemical market. Do they have a history of reliable supply and quality assurance? Engaging with established suppliers who understand pharmaceutical regulatory demands is highly recommended.

Miconazole Pricing and Availability

The price of Miconazole can vary based on purity, order volume, and supplier. As a global supplier, NINGBO INNO PHARMCHEM CO.,LTD. offers competitive pricing for high-quality Miconazole, catering to the needs of pharmaceutical manufacturers. We understand the importance of cost-effectiveness in drug production and strive to provide value without compromising on quality. Contact us for a detailed quotation and to learn more about our supply capabilities for Miconazole.