Microcrystalline Cellulose PH102: Properties and Benefits for Tablet Production
At NINGBO INNO PHARMCHEM CO.,LTD., we recognize Microcrystalline Cellulose (MCC) PH102 as a foundational excipient in modern pharmaceutical science. This versatile ingredient, derived from refined wood pulp, offers a unique combination of properties that are critical for the successful formulation of solid dosage forms, particularly tablets.
The microcrystalline cellulose properties that make it so valuable include its excellent compressibility, good flowability, and inherent inertness. These attributes directly contribute to its effectiveness as a binder, enabling tablets to hold together firmly, and as a disintegrant, facilitating their breakdown upon ingestion. The PH102 grade, in particular, is widely recognized for its balanced characteristics, making it suitable for a broad range of tablet manufacturing processes, including direct compression and wet granulation.
One of the primary benefits of MCC in drug formulation is its ability to enhance tabletability. MCC plastically deforms under compression, creating strong inter-particle bonds that result in tablets with high mechanical strength and low friability. This ensures that tablets can withstand the rigors of packaging, shipping, and handling without crumbling. Furthermore, its porous structure allows for efficient water uptake, which is essential for its function as a disintegrant. Upon contact with moisture, MCC swells, disrupting the tablet matrix and promoting rapid disintegration, which is key for optimal drug release and absorption.
As a filler or diluent, MCC provides bulk to formulations, especially those containing potent APIs that require precise dosing in small quantities. Its tasteless and odorless nature ensures that it does not interfere with the palatability or sensory profile of the medication. This makes it an ideal choice for a wide array of pharmaceutical products.
For pharmaceutical manufacturers seeking to buy microcrystalline cellulose, understanding the different grades and their specific applications is important. MCC PH102 is a workhorse excipient due to its excellent compressibility and good flow characteristics, making it a reliable choice for various tableting challenges. NINGBO INNO PHARMCHEM CO.,LTD. supplies high-quality MCC PH102, ensuring batch-to-batch consistency and performance that our clients can depend on.
The microcrystalline cellulose applications are extensive, covering everything from immediate-release tablets to more complex drug delivery systems. Its predictable behavior and compatibility with many APIs make it a go-to excipient for formulators. By leveraging the unique properties of MCC PH102, NINGBO INNO PHARMCHEM CO.,LTD. empowers its clients to develop pharmaceutical products that are not only effective but also manufacturable with greater efficiency and reliability.
Perspectives & Insights
Nano Explorer 01
“The microcrystalline cellulose properties that make it so valuable include its excellent compressibility, good flowability, and inherent inertness.”
Data Catalyst One
“These attributes directly contribute to its effectiveness as a binder, enabling tablets to hold together firmly, and as a disintegrant, facilitating their breakdown upon ingestion.”
Chem Thinker Labs
“The PH102 grade, in particular, is widely recognized for its balanced characteristics, making it suitable for a broad range of tablet manufacturing processes, including direct compression and wet granulation.”