Molecular recognition is a cornerstone of chemical analysis, diagnostics, and sensing technologies. Understanding how molecules interact, bind, and differentiate is key to developing precise analytical methods. Octakis-(6-mercapto-6-deoxy)-γ-Cyclodextrin (CAS: 180839-61-6) offers unique capabilities in this area, serving as an excellent model compound for researchers investigating these intricate processes.

The Power of Cyclodextrins in Molecular Recognition

Cyclodextrins, including derivatives like Octakis-(6-mercapto-6-deoxy)-γ-Cyclodextrin, are known for their ability to form host-guest inclusion complexes. Their toroidal structure, featuring a hydrophobic interior and a hydrophilic exterior, allows them to selectively encapsulate smaller molecules. The specific modification in this compound—the presence of eight mercapto (-SH) groups—enhances its utility in molecular recognition studies:

  • Chiral Separation: The inherent chirality of cyclodextrins, combined with the functionalization by thiol groups, can be exploited in chiral chromatography. This derivative can potentially form diastereomeric complexes with enantiomers, enabling their separation based on subtle differences in binding affinity.
  • Selective Binding Studies: The thiol groups can be further modified or used to tailor the binding properties of the cyclodextrin cavity, allowing researchers to investigate the selectivity of binding towards specific guests based on size, shape, and functional groups. This is invaluable for developing selective recognition components for sensors.
  • Investigating Thiol Interactions: As a compound rich in thiol groups, it serves as an excellent model for studying the binding mechanisms and interactions of other thiol-containing molecules, providing insights into biological processes or chemical reactions involving thiols.

Procurement for Analytical Research

For research laboratories and analytical chemists needing to buy Octakis-(6-mercapto-6-deoxy)-γ-Cyclodextrin, the procurement process should focus on:

  • Supplier Quality: Ensuring the compound is supplied with high purity (e.g., 97%+) from a reputable manufacturer is crucial for obtaining accurate and reproducible results in molecular recognition studies.
  • Availability and Pricing: Researchers often require specific quantities for experimental setup. Inquiring about product availability and requesting price quotes from reliable suppliers, especially those based in China, can help manage research budgets effectively.
  • Technical Documentation: Access to detailed specifications, CAS number (180839-61-6), and safety data is fundamental for proper experimental planning and handling.

Purchasing for Your Research Needs

When you need to acquire Octakis-(6-mercapto-6-deoxy)-γ-Cyclodextrin for your molecular recognition research, identify chemical suppliers that specialize in cyclodextrin derivatives. Engaging directly with manufacturers will allow you to discuss your specific research requirements and secure a consistent supply of this valuable analytical tool.