Moxifloxacin Synthesis: The Role of 2,3-Pyridinedicarboxylic Anhydride
The synthesis of potent and effective pharmaceuticals relies heavily on the availability of high-quality intermediates. In the realm of antibiotics, Moxifloxacin stands out as a significant fluoroquinolone, and its production pathway critically involves 2,3-Pyridinedicarboxylic Anhydride, identified by CAS No. 699-98-9. This chemical compound, also known by synonyms such as furo[3,4-b]pyridine-5,7-dione or quinolinic anhydride, serves as a foundational building block, enabling the intricate chemical transformations required to form the final Moxifloxacin molecule.
Chemical Profile and Importance for Moxifloxacin
2,3-Pyridinedicarboxylic Anhydride (C7H3NO3) possesses a molecular weight of 149.10400. Its physical properties, such as a melting point between 137-139°C and a boiling point of 334.6°C at 760 mmHg, indicate its stability under typical synthesis conditions. Crucially, for manufacturers of Moxifloxacin, the purity of this anhydride is paramount. Supplied typically as a white to yellow powder with guaranteed purity of ≥99% and a low moisture content of ≤0.3%, it ensures that the subsequent reactions proceed smoothly, minimizing by-product formation and maximizing the yield of the desired active pharmaceutical ingredient (API).
The structure of 2,3-Pyridinedicarboxylic Anhydride contains the core pyridine ring and reactive anhydride functionality, which are essential for initiating the cyclization and functionalization steps in the Moxifloxacin synthesis. By understanding the role of this specific intermediate, procurement managers and R&D scientists can better assess the quality and origin of their chemical supplies.
Sourcing Strategies for Pharmaceutical Manufacturers
For companies looking to buy 2,3-Pyridinedicarboxylic Anhydride for their Moxifloxacin production, several factors come into play. Beyond the technical specifications, the reliability of the supplier is a key consideration. Manufacturers often seek to establish long-term partnerships with suppliers who can guarantee consistent product quality, competitive pricing, and timely delivery. Many pharmaceutical firms turn to global markets, particularly China, to source such intermediates, leveraging the country's extensive chemical manufacturing infrastructure.
When exploring options to purchase CAS 699-98-9, it is advisable to request detailed specifications and Certificates of Analysis. Engaging with suppliers who can also provide support for other upstream or downstream intermediates can streamline the procurement process further. For those in the market for this critical compound, searching for a reputable '2,3-Pyridinedicarboxylic Anhydride manufacturer' or 'CAS 699-98-9 supplier' will lead to potential partners who can meet your commercial and R&D requirements.
In summary, 2,3-Pyridinedicarboxylic Anhydride is not just another chemical; it is an indispensable component in the synthesis of Moxifloxacin. Its quality directly impacts the efficacy and safety of this vital antibiotic. By focusing on sourcing from trusted manufacturers and understanding the chemical's specific role, pharmaceutical companies can ensure the robustness and efficiency of their production processes.
Perspectives & Insights
Chem Catalyst Pro
“When exploring options to purchase CAS 699-98-9, it is advisable to request detailed specifications and Certificates of Analysis.”
Agile Thinker 7
“Engaging with suppliers who can also provide support for other upstream or downstream intermediates can streamline the procurement process further.”
Logic Spark 24
“For those in the market for this critical compound, searching for a reputable '2,3-Pyridinedicarboxylic Anhydride manufacturer' or 'CAS 699-98-9 supplier' will lead to potential partners who can meet your commercial and R&D requirements.”