In the realm of solid oral dosage forms, tablets are among the most prevalent and versatile. The manufacturing of tablets relies heavily on the precise function of various excipients to ensure proper compression, disintegration, and drug release. Polyvinylpyrrolidone K30 (PVP K30), a synthetic polymer identified by CAS number 9003-39-8, plays a dual and critical role in tablet formulation as both a binder and a disintegrant. As a prominent manufacturer and supplier of high-quality pharmaceutical ingredients in China, we highlight the indispensable contributions of PVP K30 to efficient and effective tablet manufacturing.

PVP K30 as a Tablet Binder

During the granulation process for tablet manufacturing, binders are essential for holding the powdered ingredients together, forming granules that are compressible and robust. PVP K30 excels as a binder due to its excellent adhesive properties. When used in wet granulation, it forms strong bonds between particles, ensuring the integrity of the granules. This leads to:

  • Improved Flowability: Well-formed granules exhibit better flow characteristics, leading to more uniform die filling during compression.
  • Enhanced Tablet Hardness: The binding action contributes to tablets that are sufficiently hard to withstand handling and packaging without breaking.
  • Reduced Dusting: By binding fine particles, PVP K30 minimizes dust generation, which is important for operator safety and environmental control in manufacturing facilities.

Our pharmaceutical grade PVP K30, sourced from our advanced manufacturing facilities in China, is trusted by formulators worldwide for its reliable binding performance.

PVP K30 as a Disintegrant

Paradoxically, while PVP K30 binds particles together, it also aids in the rapid disintegration of the tablet once it enters the body. This property is crucial for ensuring that the API is released promptly for absorption. PVP K30 facilitates disintegration through several mechanisms:

  • Wicking Action: Its hydrophilic nature allows it to absorb moisture rapidly, promoting the swelling and subsequent breakdown of the tablet structure.
  • Particle Swelling: Upon contact with physiological fluids, PVP K30 can swell, creating internal pressure that helps to break the tablet apart.
  • Porosity Creation: Its presence can contribute to the porous structure of the tablet, allowing for better penetration of gastrointestinal fluids.

This dual functionality of binding and disintegration makes PVP K30 a highly efficient and versatile excipient. For formulators, it simplifies the formulation process and allows for greater control over tablet performance. As a leading supplier, we ensure that our PVP K30 offers optimal performance in both capacities.

Why Choose Us as Your PVP K30 Manufacturer and Supplier?

When you choose to buy Polyvinylpyrrolidone K30 from us, you benefit from:

  • Consistent Quality: Our products adhere to international pharmacopoeial standards, ensuring reliable performance in your formulations.
  • Competitive Pricing: We offer attractive prices for bulk purchases, making quality excipients accessible.
  • Robust Supply Chain: As a Chinese manufacturer, we ensure a stable and timely supply to meet your production demands.
  • Technical Support: Our team is ready to assist with formulation guidance and technical queries.

We invite all pharmaceutical companies seeking high-performance binders and disintegrants to request a quote for our Polyvinylpyrrolidone K30. Partnering with us means securing a dependable source of a critical excipient that enhances tablet manufacturability and efficacy.