N-(2,6-Dimethylphenyl)chloroacetamide, a compound known by various synonyms including 2-Chloro-N-(2,6-Dimethylphenyl)Acetamide, is a pivotal chemical entity within the pharmaceutical industry. Its importance stems primarily from its function as a key intermediate in the synthesis of complex drug molecules, most notably Ranolazine and Lidocaine. For researchers and manufacturers, a thorough understanding of its properties is essential for optimizing synthesis processes and ensuring product quality. This article details the characteristics of N-(2,6-Dimethylphenyl)chloroacetamide and its applications as a reliable building block for pharmaceutical development.

With a molecular formula of C10H12ClNO and a molecular weight of 197.661, N-(2,6-Dimethylphenyl)chloroacetamide presents a unique chemical structure that facilitates specific reactions. Physically, it appears as a white to off-white powder. Its physical and chemical characteristics are well-defined: a density of approximately 1.2±0.1 g/cm³, a boiling point of 316.8±30.0 °C at 760 mmHg, and a melting point ranging from 150-151 °C. These properties indicate a stable compound that remains solid at typical room temperatures, making it easier to handle and store in industrial settings. The flash point of 145.4±24.6 °C further adds to its safety profile during processing.

The primary application of N-(2,6-Dimethylphenyl)chloroacetamide lies in its role as a pharmaceutical intermediate. Its chloroacetamide group provides a reactive site that is instrumental in the multi-step synthesis of critical drugs. For Ranolazine, used in the treatment of chronic angina, this intermediate is indispensable for constructing its molecular framework. Similarly, Lidocaine, a widely recognized local anesthetic and antiarrhythmic, relies on the compound's specific reactivity during its synthesis. Pharmaceutical companies looking to buy this intermediate can expect a product with a minimum assay of ≥98.0%, ensuring high purity crucial for drug manufacturing.

Sourcing this essential chemical intermediate requires a dependable supplier. Many pharmaceutical manufacturers rely on specialized N-(2,6-Dimethylphenyl)chloroacetamide suppliers in China, known for their robust manufacturing capabilities and commitment to quality. When considering a purchase, attention should be paid to the manufacturer's ability to provide consistent product quality, adherence to specifications, and timely delivery. Packaging typically involves 25 kg drums, with options for customization to meet specific client needs, underscoring the flexibility available from reputable global suppliers.

The industrial significance of N-(2,6-Dimethylphenyl)chloroacetamide is directly linked to the demand for the pharmaceuticals it helps create. As the global pharmaceutical market continues to grow, driven by an increasing need for treatments for cardiovascular conditions and pain management, the demand for high-quality intermediates like this compound remains strong. For companies seeking a reliable source, partnering with a manufacturer that offers competitive pricing and a stable supply chain is crucial. If you are looking for a trusted N-(2,6-Dimethylphenyl)chloroacetamide manufacturer, exploring options from established players in the market ensures quality and efficiency in your production processes.