In the specialized field of pharmaceutical intermediates, a deep understanding of chemical properties is crucial for successful synthesis and application. N-(2-chloropyrimidin-4-yl)-N,2,3-trimethyl-2H-indazol-6-amine, identified by CAS 444731-75-3, is a key intermediate with significant value in the production of Pazopanib, an effective anti-cancer drug. This article explores its key chemical characteristics and the advantages of sourcing from established manufacturers.

The compound's basic properties include a molecular formula of C14H14ClN5 and a molecular weight of 287.75 g/mol. Typically, it is supplied as a light yellow powder with a melting point between 167-173°C. Its solubility profile, showing slight solubility in chloroform and ethyl acetate, is important for chemists planning reaction conditions. The pKa of 2.82±0.30 provides insights into its acidic properties, which can be relevant in certain reaction environments.

For pharmaceutical developers and manufacturers, identifying a reliable N-(2-chloropyrimidin-4-yl)-N,2,3-trimethyl-2H-indazol-6-amine manufacturer is paramount. We specialize in connecting clients with top-tier producers in China who guarantee a minimum purity of 99%. These manufacturers employ rigorous quality control measures throughout their synthesis processes, ensuring that the intermediate meets the demanding specifications required for pharmaceutical applications. When you buy N-(2-chloropyrimidin-4-yl)-N,2,3-trimethyl-2H-indazol-6-amine from our network, you are assured of consistent quality.

The strategic importance of this intermediate in the synthesis of Pazopanib cannot be overstated. Pazopanib's mechanism of action as a tyrosine kinase inhibitor is critical in treating advanced renal cell carcinoma and other malignancies. Therefore, the integrity of its precursors, such as CAS 444731-75-3, directly influences the drug's overall performance. As a leading CAS 444731-75-3 supplier, we aim to provide comprehensive support, including technical data and competitive pricing for bulk purchases.

For researchers and procurement specialists looking to source this vital compound, understanding its synthesis and properties is key. The reaction described in patents, involving N,2,3-trimethyl-2H-indazol-6-amine and 2,4-dichloropyrimidine, illustrates the chemical transformations involved. We invite you to contact us to obtain a quotation for N-(2-chloropyrimidin-4-yl)-N,2,3-trimethyl-2H-indazol-6-amine and discuss your specific needs. Secure your supply chain for this essential pharmaceutical intermediate with confidence.