N-(4-Bromobutyl)phthalimide (CAS 5394-18-3) is a compound of significant interest in the field of organic chemistry due to its versatile reactivity and utility as a synthetic intermediate. For research scientists and product formulators, a thorough understanding of its chemical properties is fundamental to leveraging its potential in various applications.

Physically, N-(4-Bromobutyl)phthalimide typically presents as a powder, with reported colors ranging from white to a light brown hue. Its melting point is a key characteristic, usually falling within the 76-80°C range. This solid form, combined with its specific solubility profile—soluble in ethanol but insoluble in water—dictates how it can be effectively handled and utilized in different reaction media. For procurement, understanding these physical attributes helps in selecting appropriate storage and handling protocols.

Chemically, the molecule contains a bromobutyl functional group, which is an excellent leaving group, making it highly reactive in nucleophilic substitution reactions. This characteristic is precisely why it’s a favored reagent for introducing a four-carbon chain attached to a nitrogen atom via the phthalimide protecting group. This makes it invaluable in multi-step organic synthesis, allowing for the controlled introduction of specific molecular fragments. When you buy N-(4-Bromobutyl)phthalimide, you are acquiring a tool for precise molecular construction.

One of the most cited applications is its role in the synthesis of beta-cyclodextrin derivatives. These complex carbohydrate structures have wide-ranging applications in drug delivery, catalysis, and separation technologies. The ability to modify cyclodextrins using reagents like N-(4-Bromobutyl)phthalimide opens up avenues for creating materials with tailored properties. Researchers looking to purchase this intermediate for such advanced applications should seek suppliers offering high purity grades to ensure the success of their derivatization reactions.

As a product from a chemical manufacturer, N-(4-Bromobutyl)phthalimide is available with detailed specifications. Procurement managers should verify purity levels (often stated as >98% via NMR), CAS registry number, and molecular weight (282.13 g/mol) when sourcing. For bulk orders, contacting a supplier directly for a quote is the best approach to discuss pricing, packaging, and delivery timelines. Investing in a reliable supply of this intermediate is a strategic step for any lab focused on advanced organic synthesis and material science.