N-(4-Chlorophenyl)-1,2-phenylenediamine, identified by CAS number 68817-71-0, is a versatile organic intermediate that finds critical applications in various sectors of the chemical industry. Its unique structural features, combining an ortho-phenylenediamine moiety with a chlorinated phenyl group, make it a valuable building block for synthesizing complex molecules. For researchers and industrial chemists, understanding its utility and sourcing options is key to leveraging its full potential. This article highlights the primary applications and provides guidance on how to effectively obtain this compound.

Core Applications in Synthesis

The primary value of N-(4-Chlorophenyl)-1,2-phenylenediamine lies in its role as a precursor in organic synthesis. Two prominent areas where it is utilized are:

  1. Pharmaceutical Intermediates: This compound is a crucial intermediate in the synthesis of clofazimine analogs. Clofazimine is an established drug with antibacterial properties, and its analogs are continuously explored for new therapeutic applications, including potential anti-cancer, anti-inflammatory, and anti-parasitic activities. The specific structure of N-(4-Chlorophenyl)-1,2-phenylenediamine facilitates the construction of these complex pharmaceutical agents.
  2. Dye Synthesis: It serves as a precursor for monoaminophenazine dyes. These dyes are known for their specific color properties and stability, finding use in various industrial applications such as textiles, inks, and coatings. The cyclization reaction involving this diamine allows for the formation of the phenazine chromophore, which is fundamental to these dye classes.

Why Choose High-Purity N-(4-Chlorophenyl)-1,2-phenylenediamine?

In both pharmaceutical development and dye manufacturing, the purity of the starting materials is paramount. Using high-purity N-(4-Chlorophenyl)-1,2-phenylenediamine (often exceeding 98% by HPLC) ensures:

  • Reduced formation of unwanted by-products, leading to cleaner reactions and simpler purification.
  • Improved yield of the desired end product.
  • Consistent batch-to-batch quality, crucial for regulatory compliance in pharmaceuticals and predictable performance in dyes.

When you buy N-(4-Chlorophenyl)-1,2-phenylenediamine, always prioritize suppliers who can provide detailed specifications and Certificates of Analysis.

Where to Buy and What to Consider

For researchers and manufacturers, sourcing N-(4-Chlorophenyl)-1,2-phenylenediamine requires identifying reliable manufacturers and suppliers. Companies often look for competitive pricing and stable supply chains. Many international buyers turn to established chemical suppliers in China who specialize in fine chemical intermediates. When you purchase N-(4-Chlorophenyl)-1,2-phenylenediamine, consider the supplier's reputation, their quality control processes, and their ability to meet your specific quantity requirements. Engaging with a trusted vendor ensures that you receive a product that meets your exacting standards for synthesis and research.