In the realm of fine chemicals and pharmaceutical intermediates, certain molecules stand out for their pivotal role in synthesizing complex and vital drugs. N-[5-(Diphenylphosphinoylmethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide, identified by CAS number 289042-10-0, is one such compound. It serves as a critical building block, particularly in the production of Rosuvastatin, a widely prescribed statin medication. Understanding its significance and sourcing it effectively is key for pharmaceutical manufacturers and researchers.

The chemical structure of N-[5-(Diphenylphosphinoylmethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide is characterized by its intricate arrangement of functional groups. The presence of a diphenylphosphinoylmethyl group, a 4-fluorophenyl substituent, and a substituted pyrimidine ring, coupled with a methanesulfonamide moiety, makes it a versatile precursor for specific synthetic pathways. Its precise molecular architecture is crucial for its function as an intermediate in the multi-step synthesis of Rosuvastatin. For many pharmaceutical companies, the ability to readily purchase this compound at a high level of purity is a non-negotiable requirement.

When seeking this specific chemical, potential buyers often turn to specialized suppliers who can guarantee quality and availability. China has emerged as a leading global source for such fine chemicals and pharmaceutical intermediates. A reputable manufacturer in China, such as NINGBO INNO PHARMCHEM CO.,LTD., can provide N-[5-(Diphenylphosphinoylmethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide with high purity standards (often ≥99.0%). This ensures that the intermediate integrates seamlessly into complex synthesis routes, minimizing side reactions and maximizing the yield of the desired API.

For procurement managers and R&D scientists, identifying a reliable supplier is paramount. This involves looking for companies that not only offer competitive pricing but also maintain stringent quality control protocols and provide comprehensive documentation. Obtaining a detailed quote and understanding the product's specifications are crucial steps before making a purchase decision. The availability of this intermediate in various quantities, from laboratory research scales to commercial production volumes, is also a key factor. Companies seeking this building block can enquire directly with manufacturers to discuss their specific needs and ensure a consistent supply.

In summary, N-[5-(Diphenylphosphinoylmethyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl]-N-methylmethanesulfonamide (CAS 289042-10-0) is a critical chemical building block for the pharmaceutical industry. Its reliable sourcing from qualified manufacturers, particularly those in China, ensures the efficient and cost-effective production of essential medicines like Rosuvastatin. Understanding the importance of purity, consistency, and supplier reliability is key to successful procurement in this specialized sector.