N-Benzyl-N-methylethanolamine (CAS 101-98-4) is a chemical compound widely utilized in various research and industrial applications, particularly in organic synthesis and pharmaceutical development. For laboratory scientists, formulators, and procurement specialists, a clear understanding of its chemical properties and safe handling practices is crucial. This guide provides essential information for effectively working with this versatile chemical.

Key Chemical Properties
N-Benzyl-N-methylethanolamine, with the molecular formula C10H15NO and a molecular weight of approximately 165.23 g/mol, is typically described as a light yellow liquid. Its physical state is important for handling and storage considerations. Key properties reported include a density of around 1.017 g/mL at 25°C and a boiling point of 95-105°C at 2 mm Hg. The refractive index is noted as n20/D 1.529. Its flash point is greater than 230°F, indicating a relatively low flammability risk under normal conditions, although standard precautions should always be observed.

Solubility and Storage Recommendations
This compound shows slight solubility in chloroform and methanol, which is relevant for its use in various solvent systems during synthesis or purification. For maintaining its stability and efficacy, N-Benzyl-N-methylethanolamine should be stored in a tightly closed container in a cool, dry, and well-ventilated area, away from incompatible substances. Proper storage conditions are critical for ensuring the longevity and purity of the product, especially when purchased in bulk from a supplier.

Safety and Handling Precautions
Safety is paramount when handling any chemical. N-Benzyl-N-methylethanolamine is classified with hazard codes like Xi, indicating it can cause irritation. Specifically, hazard statements mention skin irritation (H315), serious eye irritation (H319), and potential respiratory irritation (H335). Therefore, when working with this compound, it is essential to wear appropriate personal protective equipment (PPE), including safety goggles, chemical-resistant gloves, and lab coats. Adequate ventilation, such as working in a fume hood, is also recommended to minimize exposure to vapors. In case of contact, immediate flushing with water is advised, and medical attention should be sought if irritation persists. Always refer to the Safety Data Sheet (SDS) provided by the manufacturer or supplier for detailed safety information.

Applications in Synthesis and Research
Professionals seeking to buy N-Benzyl-N-methylethanolamine will find its applications particularly valuable in pharmaceutical intermediate synthesis. It is used in the preparation of dihydropyrimidinones and in the synthesis of pseudopeptides, both of which are critical areas of drug discovery. Its surfactant properties also lend themselves to use as an adsorbent in chromatography, aiding in protein purification. For researchers and formulators, understanding these applications, alongside the chemical properties, helps in optimizing its use.

When procuring N-Benzyl-N-methylethanolamine (CAS 101-98-4), always prioritize sourcing from reputable manufacturers and suppliers who provide comprehensive technical and safety data. This ensures you receive a high-quality product that can be handled and utilized safely and effectively for your intended applications.