N-Benzyloxycarbonyl-L-valine, scientifically identified by CAS 1149-26-4, is a protected amino acid that holds significant importance in various chemical synthesis applications, particularly within the pharmaceutical and biotechnology sectors. Often referred to as Z-L-Valine or Cbz-Val-OH, this compound is prized for its role as a key intermediate, facilitating complex molecular constructions. For procurement specialists and researchers, understanding its properties and how to source it reliably, especially from China suppliers, is paramount.

The essential properties of N-Benzyloxycarbonyl-L-valine contribute to its utility. It typically appears as a white to off-white crystalline powder, with a melting point generally falling between 53-64°C. Its molecular formula is C13H17NO4, and its molecular weight is approximately 251.28 g/mol. The presence of the benzyloxycarbonyl (Cbz) protecting group on the alpha-amino function of L-valine allows for controlled peptide bond formation and subsequent selective deprotection, typically through catalytic hydrogenation. This makes it a staple in peptide synthesis and the production of various pharmaceutical agents.

When looking to buy N-Benzyloxycarbonyl-L-valine, sourcing from China suppliers can offer significant advantages in terms of cost and availability. However, it is crucial to partner with manufacturers who adhere to strict quality control measures. Look for suppliers who can provide Certificates of Analysis (CoA) confirming high purity (often exceeding 98% by HPLC) and appropriate optical activity. Companies specializing in amino acid derivatives and pharmaceutical intermediates often have established quality systems, ensuring their products meet international standards like USP or BP.

The pricing for N-Benzyloxycarbonyl-L-valine from China manufacturers is generally competitive, especially for bulk orders. It is advisable to request detailed quotes that include FOB China prices, minimum order quantities (MOQs), and estimated delivery times. Building a relationship with a trusted supplier can also ensure a more stable and predictable supply chain, which is critical for ongoing research and manufacturing projects. For example, inquiring about the latest price for Z-L-Valine or Cbz-Val-OH in larger quantities can often reveal cost efficiencies.

In conclusion, N-Benzyloxycarbonyl-L-valine is a vital chemical intermediate. By understanding its key properties and implementing a rigorous sourcing strategy that involves vetting China suppliers for quality, purity, and competitive pricing, organizations can effectively secure this essential compound for their demanding synthesis needs.