N-Boc-3-Pyrrolidinone: Properties, Synthesis, and Supplier Selection
N-Boc-3-pyrrolidinone, bearing the CAS number 101385-93-7, is a fundamental compound in modern organic chemistry, serving as a versatile building block for sophisticated synthesis. Its utility is recognized across academic research and industrial applications, particularly within the pharmaceutical and fine chemical sectors. Understanding its chemical properties, common synthetic uses, and how to select an appropriate supplier are critical steps for any research scientist or procurement manager aiming to leverage this compound effectively.
Chemically, N-Boc-3-pyrrolidinone is characterized by its pyrrolidinone ring functionalized with a tert-butoxycarbonyl (Boc) protecting group. This structural feature imparts specific reactivity, making it ideal for controlled synthetic transformations. Typically available with a purity of 97% GC or higher, it presents as a colorless liquid or a white solid, with a melting point typically between 34-38°C. Its solubility profile, often noted as insoluble in water but soluble in common organic solvents, dictates its handling and reaction conditions. For those looking to buy N-Boc-3-pyrrolidinone, these properties are key indicators of quality and suitability for their intended applications, such as the synthesis of heterocyclic compounds or precursors for biologically active molecules.
The synthetic utility of N-Boc-3-pyrrolidinone is extensive. It is frequently employed in medicinal chemistry as an intermediate for drug discovery, particularly in the development of agents targeting neurological and psychiatric disorders. Its ability to introduce specific structural motifs allows chemists to design and synthesize novel drug candidates with enhanced efficacy and reduced side effects. Beyond pharmaceuticals, it finds application in materials science and the development of specialized chemicals. When seeking to purchase this compound, researchers often look for suppliers who can provide comprehensive technical data and consistent product quality to support their ongoing projects.
Selecting the right supplier for N-Boc-3-pyrrolidinone is a crucial decision. Procurement managers should prioritize manufacturers and distributors who offer transparency in their product specifications, robust quality control measures, and reliable delivery services. Companies that provide detailed product information, safety data sheets (SDS), and certificates of analysis (CoA) are generally more trustworthy. Engaging with a reputable N-Boc-3-pyrrolidinone manufacturer, especially one based in China known for its competitive pricing and production capabilities, can significantly benefit research and manufacturing operations. Ensuring a stable supply chain for such a critical intermediate is vital for the continuity of R&D and production.
Perspectives & Insights
Quantum Pioneer 24
“It is frequently employed in medicinal chemistry as an intermediate for drug discovery, particularly in the development of agents targeting neurological and psychiatric disorders.”
Bio Explorer X
“Its ability to introduce specific structural motifs allows chemists to design and synthesize novel drug candidates with enhanced efficacy and reduced side effects.”
Nano Catalyst AI
“Beyond pharmaceuticals, it finds application in materials science and the development of specialized chemicals.”