In the dynamic field of chemical research, access to specialized, high-purity compounds is crucial for scientific advancement. N-Boc-4,4-difluoro-L-proline (CAS 203866-15-3) is one such compound that has garnered significant attention for its unique properties and applications, particularly in medicinal chemistry and pharmaceutical development. As a leading supplier of fine chemicals, understanding the precise needs of researchers is our priority.

The Unique Chemistry of N-Boc-4,4-difluoro-L-proline

N-Boc-4,4-difluoro-L-proline is a protected derivative of the amino acid proline, distinguished by the presence of two fluorine atoms at the 4-position of its pyrrolidine ring. The tert-butoxycarbonyl (Boc) group serves as a convenient protecting group, facilitating its integration into various synthetic schemes. Its chemical formula, C10H15F2NO4, and molecular weight of 251.23 g/mol, make it a well-defined building block for complex molecule synthesis.

Key Applications Driving Demand

The utility of N-Boc-4,4-difluoro-L-proline stems from the advantageous properties conferred by fluorine:

  • Enhanced Metabolic Stability: The strong carbon-fluorine bond can protect adjacent parts of a molecule from metabolic degradation, leading to longer drug half-lives.
  • Modulated Lipophilicity: Fluorine substitution can fine-tune a molecule's lipophilicity, impacting its absorption, distribution, and cellular penetration.
  • Conformational Control: In peptide synthesis, the difluorinated proline can influence the peptide backbone's conformation, aiding in the study of protein folding and function.
  • Structure-Activity Relationship (SAR) Studies: It's a key component in SAR studies for various drug classes, including potential anti-tumor agents and kinase inhibitors, allowing researchers to systematically explore the impact of fluorination.

For researchers aiming to buy N-Boc-4,4-difluoro-L-proline, understanding these benefits is crucial for maximizing its potential in their projects. The price of N-Boc-4,4-difluoro-L-proline reflects its specialized nature and the precision required in its synthesis.

Why Choose a Trusted Manufacturer?

The effectiveness of N-Boc-4,4-difluoro-L-proline in research is directly tied to its purity and quality. As a dedicated manufacturer, we adhere to stringent quality control protocols to ensure our product consistently meets a purity of ≥97%. This commitment is vital for obtaining reliable and reproducible results in complex synthetic pathways and biological assays. Partnering with a reputable supplier like us means:

  • Guaranteed Product Quality: Ensuring high purity and consistent specifications for critical research applications.
  • Reliable Supply: Maintaining adequate stock and production capacity to meet the ongoing demands of research and development.
  • Competitive Pricing: Offering value for money, especially for bulk purchases of this specialized chemical.
  • Technical Support: Providing access to product information and expert advice to facilitate its effective use.

Conclusion

N-Boc-4,4-difluoro-L-proline (CAS 203866-15-3) is a valuable asset for chemists and pharmacologists engaged in cutting-edge research. Its unique fluorinated structure offers distinct advantages in drug design and biochemical studies. By prioritizing quality and reliability when you purchase this essential compound, you ensure the success and integrity of your scientific endeavors. We are your trusted source for this advanced chemical building block.