Understanding N-(Bromomethyl)phthalimide Purity and Specifications for Synthesis
For any chemical synthesis, especially in the pharmaceutical sector, understanding the purity and specifications of your raw materials is critical. N-(Bromomethyl)phthalimide (CAS: 5332-26-3) is no exception. As a key intermediate, its quality directly impacts the success of downstream reactions and the integrity of the final product. This article provides insights into the crucial specifications and properties of N-(Bromomethyl)phthalimide that procurement specialists and research chemists should consider.
N-(Bromomethyl)phthalimide is typically supplied as a white to off-white solid, with a melting point range usually between 152-155 °C. The most important specification for its use as a pharmaceutical intermediate, such as in the synthesis of Netarsudil, is its purity. High-purity N-(Bromomethyl)phthalimide, commonly assessed by High-Performance Liquid Chromatography (HPLC), should ideally be greater than 98%. Lower purity levels can introduce unwanted side reactions or contaminants, potentially compromising the efficacy and safety of the final drug substance.
Other critical properties include its molecular formula (C9H6BrNO2) and molecular weight (approximately 240.05 g/mol). Understanding its solubility and stability is also important; while it generally decomposes in water, it is sensitive to moisture and light, requiring appropriate storage conditions. Suppliers like NINGBO INNO PHARMCHEM CO.,LTD. provide detailed technical data sheets and Certificates of Analysis (CoA) that outline these specifications, ensuring transparency and product assurance.
When you decide to buy N-(Bromomethyl)phthalimide, it is essential to verify these specifications with your chosen manufacturer. A reliable supplier will not only guarantee high purity but also ensure consistency across batches, which is vital for reproducible synthesis outcomes. Whether you are using it as a building block for complex organic molecules or as a specific Netarsudil intermediate, consistent quality is key.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to delivering N-(Bromomethyl)phthalimide that meets the highest industry standards. Our manufacturing processes are designed to achieve and maintain exceptional purity, supporting the critical needs of our pharmaceutical and fine chemical clients. We offer comprehensive product documentation to facilitate your quality assurance processes.
In conclusion, always prioritize purity and detailed specifications when procuring N-(Bromomethyl)phthalimide. By working with trusted manufacturers who provide transparent documentation, you can ensure the success of your chemical synthesis projects. We invite you to contact us to discuss your specific requirements and to source high-quality N-(Bromomethyl)phthalimide.
Perspectives & Insights
Silicon Analyst 88
“Lower purity levels can introduce unwanted side reactions or contaminants, potentially compromising the efficacy and safety of the final drug substance.”
Quantum Seeker Pro
“Other critical properties include its molecular formula (C9H6BrNO2) and molecular weight (approximately 240.”
Bio Reader 7
“Understanding its solubility and stability is also important; while it generally decomposes in water, it is sensitive to moisture and light, requiring appropriate storage conditions.”