In the highly regulated and quality-sensitive field of pharmaceutical manufacturing, the reliability and purity of chemical intermediates are paramount. N-Carbobenzyloxy-L-valine, known by its CAS number 1149-26-4, stands as a critical pharmaceutical intermediate, underpinning the synthesis of numerous vital medications. Its importance stems from its role as a protected chiral amino acid derivative, essential for creating complex molecular structures with high precision.

The production of N-Carbobenzyloxy-L-valine involves a precise chemical synthesis, typically reacting L-valine with benzyl chloroformate under controlled alkaline conditions. NINGBO INNO PHARMCHEM CO.,LTD. specializes in the manufacturing of this compound, adhering to stringent quality control measures. Our facilities employ advanced process development, including continuous flow technology, to ensure consistent product quality, high yields, and operational safety. The appearance of our N-Carbobenzyloxy-L-valine is a pure white to off-white crystalline powder, with a guaranteed assay purity of ≥99.0%, meeting the rigorous demands of pharmaceutical applications.

The significance of N-Carbobenzyloxy-L-valine as a pharmaceutical intermediate is amplified by its application in the synthesis of prodrugs like Valaciclovir and Valganciclovir. These drugs are vital for treating viral infections, and the L-valine ester moiety, introduced via N-Carbobenzyloxy-L-valine, plays a crucial role in enhancing their oral bioavailability and therapeutic efficacy. The careful protection offered by the N-Carbobenzyloxy group ensures that the L-valine component can be precisely incorporated into the drug molecule without degradation or unwanted side reactions.

Furthermore, N-Carbobenzyloxy-L-valine serves as a versatile building block in peptide synthesis and chiral chemistry. Its defined stereochemistry and the protective nature of the Cbz group make it ideal for constructing complex peptides and enantiomerically pure compounds. This versatility extends to its use in drug discovery research, where it is employed in the synthesis of libraries of novel compounds for screening against various biological targets.

As a leading N-Carbobenzyloxy-L-valine supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. is committed to ensuring a stable and reliable supply chain for the pharmaceutical industry. We understand the critical nature of timely delivery and consistent quality. Our robust manufacturing capabilities and dedication to customer service make us a trusted partner for companies worldwide seeking high-quality pharmaceutical intermediates. For any inquiries or to source N-Carbobenzyloxy-L-valine (CAS 1149-26-4) for your pharmaceutical manufacturing needs, NINGBO INNO PHARMCHEM CO.,LTD. is your reliable partner.