For procurement managers and R&D professionals in the pharmaceutical and fine chemical sectors, sourcing key intermediates like N-Cbz-D-glutamic Acid Alpha-benzyl Ester (CAS: 65706-99-2) requires a meticulous approach. Balancing quality, cost, and supply chain reliability is paramount. This article explores these critical aspects, highlighting the advantages of engaging with Chinese manufacturers for this essential chemical.

Understanding the Product: N-Cbz-D-glutamic Acid Alpha-benzyl Ester

This compound is a protected derivative of D-glutamic acid, widely employed as a chiral building block and a crucial intermediate in peptide synthesis and pharmaceutical manufacturing. Key specifications typically include:

  • Chemical Name: N-Cbz-D-glutamic acid alpha-benzyl ester
  • CAS Number: 65706-99-2
  • Molecular Formula: C20H21NO6
  • Molecular Weight: 371.38 g/mol
  • Appearance: White powder
  • Purity: Typically 97% or higher, ensuring suitability for sensitive syntheses.
  • Solubility: Soluble in methanol and acetic acid.
  • Storage: Recommended to be stored sealed at room temperature in a dry environment.

These properties are essential for its role in creating complex molecules with specific stereochemistry.

The Quality Imperative for B2B Buyers

In the B2B chemical market, particularly for pharmaceutical intermediates, quality is non-negotiable. A purity of 97% means minimal impurities, which is critical for successful downstream reactions and the integrity of the final product. Buyers must ensure that any potential supplier, especially those looking to buy this intermediate, provides a detailed Certificate of Analysis (CoA) confirming these specifications. Reputable manufacturers also offer technical support and are transparent about their quality control processes.

Strategic Advantage: Sourcing from China

China has become a global leader in chemical manufacturing, offering significant advantages for B2B buyers of N-Cbz-D-glutamic Acid Alpha-benzyl Ester:

  • Competitive Pricing: Due to economies of scale and efficient production, Chinese manufacturers can offer this intermediate at highly competitive prices, allowing businesses to optimize their procurement budgets.
  • Scalable Production: Chinese factories are equipped to handle both small-scale R&D orders and large-volume industrial production, ensuring supply continuity as projects evolve.
  • Growing Quality Standards: Leading Chinese chemical companies have invested heavily in advanced manufacturing technologies and robust quality management systems, increasingly meeting and exceeding international standards.

When making a purchase decision, it is advisable to request free samples for internal testing to validate quality and performance before committing to larger orders.

Ensuring Supply Chain Reliability

Beyond quality and price, supply chain reliability is crucial. Partnering with established manufacturers in China often means working with suppliers experienced in international logistics, export regulations, and timely delivery. Clear communication channels and responsive customer service are key indicators of a reliable partner.

In conclusion, N-Cbz-D-glutamic Acid Alpha-benzyl Ester is a vital intermediate for numerous chemical synthesis applications. By focusing on high purity, competitive pricing, and supply chain dependability, and by strategically sourcing from qualified Chinese manufacturers, businesses can ensure the efficient and successful execution of their projects.