N,N'-Disuccinimidyl Carbonate (DSC): A Versatile Reagent for Chemical Synthesis
In the intricate world of chemical synthesis, certain reagents stand out for their versatility and efficacy across a range of applications. N,N'-Disuccinimidyl Carbonate (DSC), identified by CAS Number 74124-79-1, is one such compound. As a highly effective coupling reagent and a safer alternative to phosgene, DSC plays a crucial role in the formation of amide bonds, ureas, and carbamates. Its utility spans across fields such as peptide synthesis, bioconjugation, and specialty chemical production. For scientists and procurement specialists aiming to buy high-quality DSC, understanding its properties and identifying dependable manufacturers is key.
N,N'-Disuccinimidyl Carbonate's primary mechanism of action involves activating carboxyl groups by forming reactive N-hydroxysuccinimide (NHS) esters. These intermediates readily react with nucleophiles, most notably primary amines, to create stable amide linkages. This reactivity is fundamental to peptide synthesis, where it enables the sequential addition of amino acids to build complex peptide chains. The purity of DSC is a critical factor; typically, researchers seek products with ≥99% purity to ensure minimal side reactions and maximize the yield of desired products. When you plan to buy DSC, always verify its specifications.
The global chemical supply chain offers numerous options for sourcing DSC, with manufacturers in China often providing competitive pricing and substantial production capacities. For businesses and research institutions, sourcing from reputable Chinese suppliers, such as NINGBO INNO PHARMCHEM CO.,LTD., can offer a strategic advantage in terms of cost and availability. It is essential, however, to ensure that these suppliers maintain rigorous quality control standards and provide comprehensive documentation like Certificates of Analysis (CoA) and Material Safety Data Sheets (MSDS) to confirm product quality and safe handling.
The versatility of DSC extends beyond its well-established use in peptide synthesis. It is widely employed in bioconjugation, a field focused on linking biomolecules for therapeutic or diagnostic purposes. For example, DSC can be used to attach labels to proteins or to create antibody-drug conjugates (ADCs). Its role as a phosgene analogue also makes it valuable in synthesizing custom organic molecules for various research applications. Researchers looking to buy DSC for these diverse applications will benefit from suppliers who understand the varied needs of the scientific community.
When procuring N,N'-Disuccinimidyl Carbonate, it is prudent for procurement managers to engage with suppliers who offer excellent customer support, including prompt sample provision for initial testing and validation. A reliable partner will be transparent about their manufacturing processes and quality assurance measures. For organizations requiring bulk quantities, establishing a long-term relationship with a trusted chemical manufacturer can ensure consistent supply and competitive pricing, supporting ongoing projects and operational efficiency.
In conclusion, N,N'-Disuccinimidyl Carbonate is a remarkably versatile reagent essential for modern chemical synthesis. Its role in peptide synthesis, bioconjugation, and the development of new organic compounds underscores its importance. By prioritizing high purity and sourcing from reliable manufacturers, researchers and procurement professionals can effectively leverage DSC to achieve their scientific and commercial goals. Contact us today to discuss your requirements and to get a quotation for N,N'-Disuccinimidyl Carbonate.
Perspectives & Insights
Bio Analyst 88
“N,N'-Disuccinimidyl Carbonate (DSC), identified by CAS Number 74124-79-1, is one such compound.”
Nano Seeker Pro
“As a highly effective coupling reagent and a safer alternative to phosgene, DSC plays a crucial role in the formation of amide bonds, ureas, and carbamates.”
Data Reader 7
“Its utility spans across fields such as peptide synthesis, bioconjugation, and specialty chemical production.”