In the realm of fine chemicals and advanced organic synthesis, specific building blocks play pivotal roles in enabling complex molecular constructions. Nalpha-Fmoc-Ndelta-Boc-L-ornithine (CAS: 109425-55-0) is a prime example of such a versatile intermediate, finding widespread application primarily within the peptide synthesis sector, which underpins much of modern pharmaceutical and biotechnological research. This article explores its chemical characteristics, diverse applications, and the advantages of securing this compound from a reputable chemical manufacturer.

Chemical Profile and Synthesis Utility

Nalpha-Fmoc-Ndelta-Boc-L-ornithine is a protected derivative of L-ornithine, featuring a robust Fmoc group on the alpha-amino terminus and a Boc group on the delta-amino side chain. This dual protection strategy is the key to its utility in sequential synthesis. The chemical formula C25H30N2O6 and a molecular weight of approximately 454.52 g/mol define its structure. Typically supplied as a white powder, the purity of Nalpha-Fmoc-Ndelta-Boc-L-ornithine is critical. Manufacturers often specify purities of 95% to over 98% (verified by HPLC), ensuring that researchers and formulators can achieve reliable reaction outcomes without interference from impurities.

The strategic placement of these protecting groups allows chemists to selectively deprotect and react either the alpha-amino or delta-amino group, facilitating controlled chain elongation in peptide synthesis. This precision is essential for creating specific amino acid sequences required for therapeutic peptides, diagnostic agents, and other complex organic molecules.

Broad Applications in Chemical Manufacturing

While most prominently used in peptide synthesis, the versatile nature of Nalpha-Fmoc-Ndelta-Boc-L-ornithine makes it valuable in other chemical synthesis contexts:

  1. Pharmaceutical Intermediates: It serves as a key starting material or intermediate in the synthesis of various active pharmaceutical ingredients (APIs) that incorporate ornithine residues or modified amino acid structures.
  2. Biochemical Reagent Development: Researchers utilize it to create specialized biochemical tools, such as labeled peptides or probes for studying biological pathways.
  3. Organic Synthesis Building Block: Beyond peptides, its functional groups and chiral center can be leveraged in the synthesis of other complex organic molecules where controlled functionalization is required.
  4. Custom Synthesis Projects: Companies specializing in custom synthesis rely on such well-defined intermediates to fulfill specific client requirements for novel compounds.

Choosing Your Manufacturer and Supplier

For any organization looking to buy Nalpha-Fmoc-Ndelta-Boc-L-ornithine, selecting a reliable manufacturer and supplier is paramount. NINGBO INNO PHARMCHEM CO.,LTD. stands as a distinguished manufacturer and supplier of high-quality chemical intermediates. We are committed to providing Nalpha-Fmoc-Ndelta-Boc-L-ornithine with exceptional purity, consistency, and competitive pricing. Our goal is to support your chemical synthesis needs efficiently. We encourage you to contact us for a quote and sample to experience the quality and reliability we offer.