Navigating Chemical Synthesis: The Versatility of N-Carbobenzyloxy-L-alanine
The landscape of modern chemical synthesis is characterized by intricate multi-step processes, where the selection of appropriate building blocks and intermediates is crucial for success. N-Carbobenzyloxy-L-alanine (CAS 1142-20-7), often referred to as Z-Ala-OH, exemplifies the versatility and strategic importance of protected amino acids in achieving targeted molecular transformations.
Z-Ala-OH is an L-alanine derivative featuring a carbobenzyloxy (Z) protecting group on its amino function. This modification is fundamental to its utility in organic chemistry. The Z group effectively masks the reactive amine, allowing chemists to perform selective reactions elsewhere on the molecule or to couple Z-Ala-OH with other activated amino acids or peptides without interference from the amine. This controlled reactivity is particularly valuable in solid-phase peptide synthesis (SPPS) and solution-phase peptide coupling, where precise sequential addition of amino acids is required to build complex peptide chains.
Beyond peptide synthesis, the versatility of N-Carbobenzyloxy-L-alanine extends to its use as a chiral intermediate in the synthesis of pharmaceuticals and other fine chemicals. Its inherent chirality, derived from the L-alanine backbone, can be preserved and transferred into target molecules, which is often critical for biological activity in drug discovery. The Z group's stability under various reaction conditions and its relatively straightforward removal via catalytic hydrogenation or other methods add to its appeal as a synthetically useful intermediate.
For scientists and procurement managers aiming to leverage the capabilities of Z-Ala-OH, sourcing from a reliable manufacturer is key. As a leading supplier of N-Carbobenzyloxy-L-alanine (CAS 1142-20-7) from China, we provide materials that meet the high purity and consistency demands of advanced chemical synthesis. Understanding the applications and properties of this compound allows our clients to optimize their synthetic strategies. Whether you are exploring new peptide sequences or developing novel organic compounds, a dependable source for Z-Ala-OH is indispensable.
We are committed to facilitating complex chemical synthesis by providing high-quality N-Carbobenzyloxy-L-alanine. We invite you to learn more about our product specifications and to request a quote for your specific needs. By partnering with us, you ensure access to a versatile intermediate that can significantly enhance the efficiency and success of your synthetic endeavors.
Perspectives & Insights
Logic Thinker AI
“The landscape of modern chemical synthesis is characterized by intricate multi-step processes, where the selection of appropriate building blocks and intermediates is crucial for success.”
Molecule Spark 2025
“N-Carbobenzyloxy-L-alanine (CAS 1142-20-7), often referred to as Z-Ala-OH, exemplifies the versatility and strategic importance of protected amino acids in achieving targeted molecular transformations.”
Alpha Pioneer 01
“Z-Ala-OH is an L-alanine derivative featuring a carbobenzyloxy (Z) protecting group on its amino function.”