For professionals engaged in chemical synthesis, a thorough understanding of the properties of the materials they work with is fundamental to success. 5-Chlorothiophene-2-carbonyl Chloride (CAS 42518-98-9) is a vital organic intermediate whose characteristics dictate its handling, reactivity, and application in pharmaceutical and fine chemical synthesis. As a leading manufacturer and supplier, we provide these critical details to empower our B2B clients.

Key Physicochemical Properties:

  • Appearance: Typically described as a colorless to pale yellow liquid or oil. This visual cue is important for initial quality assessment upon receipt.
  • Molecular Formula: C5H2Cl2OS. This formula indicates the precise atomic composition, crucial for stoichiometric calculations in synthesis.
  • Molecular Weight: 181.04 g/mol. Essential for determining molar quantities in reactions.
  • Melting Point: Approximately 4°C. This low melting point suggests it may be encountered as a liquid at room temperature, simplifying handling in some applications.
  • Boiling Point: 122-127°C at 16 Torr. This data is critical for purification processes such as distillation and for understanding its volatility.
  • Density: 1.50 g/cm³. This value is useful for volume-to-mass conversions.
  • Solubility: Slightly soluble in water, but soluble in organic solvents like chloroform and methanol. This dictates suitable reaction media and purification techniques. Its slight solubility in water also highlights its moisture sensitivity.
  • Stability: It is hygroscopic and moisture-sensitive, meaning it can absorb moisture from the air and degrade. Proper storage under inert gas (like nitrogen or argon) at refrigerated temperatures (2-8°C) is recommended by many sources to maintain its integrity.

Understanding these properties is crucial for procurement managers and R&D scientists to ensure optimal use and safe handling. When you buy 5-Chlorothiophene-2-carbonyl Chloride from a reliable supplier, you receive detailed specifications that aid in process development. Its reactivity as an acyl chloride means it readily reacts with nucleophiles, making it a potent acylating agent for forming amides and esters – key reactions in drug synthesis. This reactivity also necessitates careful handling to avoid unwanted side reactions or decomposition.

We encourage you to purchase this intermediate from a trusted manufacturer to ensure you receive material that meets these described properties. Our commitment to quality means you can rely on the specifications provided for your critical syntheses. When considering the price, remember that consistency in these properties directly impacts the efficiency and success of your downstream processes. Contact us for a quote and to discuss your specific requirements for 5-Chlorothiophene-2-carbonyl Chloride.

By thoroughly understanding and respecting the properties of 5-Chlorothiophene-2-carbonyl Chloride, chemists can effectively leverage its capabilities in developing innovative pharmaceutical compounds. Partner with us for quality and expertise in chemical sourcing.