In the dynamic field of chemistry, precise control over molecular synthesis is paramount. Cross-coupling reactions, particularly the Suzuki-Miyaura coupling, have revolutionized how chemists construct complex molecules. At the heart of many such reactions lies the versatile reagent, 4-Nitrophenylboronic acid (CAS: 24067-17-2). This article delves into its role in these critical transformations and highlights the importance of sourcing from a reputable manufacturer.

The Power of Boronic Acids in Coupling Reactions

4-Nitrophenylboronic acid, identified by its CAS number 24067-17-2, is an arylboronic acid derivative. Its chemical formula is C6H6BNO4, and it typically appears as a white to yellow crystalline powder with a molecular weight of 166.93 g/mol. The boronic acid moiety (-B(OH)2) is key to its reactivity, enabling it to participate efficiently in palladium-catalyzed cross-coupling reactions. These reactions are celebrated for their high yields, functional group tolerance, and stereoselectivity, making them indispensable tools for synthetic chemists.

Applications in Advanced Synthesis

The utility of 4-Nitrophenylboronic acid in Suzuki-Miyaura cross-coupling reactions is well-established. It serves as an aryl donor, coupling with aryl or vinyl halides to form new carbon-carbon bonds. This process is foundational in the synthesis of biaryl compounds, which are prevalent in many pharmaceutical agents, advanced materials, and fine chemicals. Researchers often seek to buy 4-nitrophenylboronic acid for its reliable performance in these reactions, particularly when developing new drug candidates or optimizing existing synthetic routes.

Beyond Suzuki coupling, this compound is also employed in other transition metal-catalyzed reactions, such as ruthenium-catalyzed direct arylation. Its specific electronic properties, influenced by the nitro group, can also tune the reactivity and selectivity of these transformations, offering chemists greater control over their synthetic outcomes.

Choosing the Right Supplier: The China Advantage

For businesses requiring consistent access to high-quality 4-Nitrophenylboronic acid, partnering with a reliable supplier in China is often the most strategic choice. Chinese chemical manufacturers have developed robust production capabilities and stringent quality control systems. By choosing to purchase 4-nitrophenylboronic acid from a dedicated manufacturer, you can ensure product purity, batch-to-batch consistency, and competitive pricing. This is particularly vital for R&D scientists and procurement managers who depend on the integrity of their raw materials for successful project outcomes.

As a leading producer, we are committed to providing excellent quality 4-Nitrophenylboronic acid, backed by comprehensive technical data. We understand the critical nature of these reagents and strive to offer not only competitive 4-nitrophenylboronic acid price but also exceptional customer support. We invite you to contact us for your sourcing needs and to explore how our reliable supply can benefit your ongoing research and production.