For professionals in the chemical and pharmaceutical industries, efficient procurement of specialized intermediates is critical. CAS 22245-83-6, known scientifically as 2-Hydroxy-3-trifluoromethylpyridine, is one such compound that demands careful sourcing due to its role in advanced synthesis. This guide provides insights for buyers navigating the market for this essential chemical.

Understanding CAS 22245-83-6: Properties and Applications

2-Hydroxy-3-trifluoromethylpyridine is a fluorinated pyridine derivative characterized by its molecular formula C6H4F3NO and a molecular weight of approximately 163.10. It typically presents as an off-white crystalline powder and possesses a melting point in the range of 150-153°C. Its key features include:

  • Trifluoromethyl Group: This substituent enhances lipophilicity and metabolic stability, making it highly valuable in drug design and agrochemical development.
  • Pyridine Ring with Hydroxyl Group: These elements provide sites for further chemical modification, enabling its use as a versatile building block in organic synthesis.

Its primary applications lie in serving as an intermediate for:

  • Pharmaceuticals: Facilitating the synthesis of novel drug candidates with improved efficacy and pharmacokinetic profiles.
  • Agrochemicals: Contributing to the development of advanced pesticides and herbicides that offer better performance and environmental stability.

Market Dynamics and Sourcing from China

The global demand for 2-Hydroxy-3-trifluoromethylpyridine has led to a competitive market, with China playing a pivotal role as a major manufacturing hub for specialty chemicals. When you need to buy CAS 22245-83-6, several factors are crucial to consider:

  • Supplier Reputation: Prioritize manufacturers with a proven track record in producing high-purity chemicals.
  • Purity Assurance: Always verify the assay specification, aiming for u226598.0% to ensure consistent synthesis results.
  • Pricing and Availability: Secure competitive pricing by obtaining multiple quotes from reliable suppliers. Ensure they can meet your required order volumes and delivery timelines.
  • Technical Documentation: Access to MSDS and Certificates of Analysis (CoA) is essential for compliance and safe handling.

As a procurer, identifying a trusted 2-Hydroxy-3-trifluoromethylpyridine supplier in China can streamline your sourcing process. These suppliers often leverage advanced manufacturing techniques and economies of scale to offer quality products at competitive price points.

Making an Informed Purchase Decision

When engaging with potential vendors, direct inquiries about bulk purchase options, lead times, and quality control measures are recommended. For critical R&D projects or large-scale production, establishing a strong relationship with a dependable manufacturer is key to ensuring a consistent and high-quality supply of CAS 22245-83-6.

In essence, navigating the market for CAS 22245-83-6 requires a strategic approach to sourcing. By focusing on quality, reliability, and competitive pricing from established manufacturers, you can confidently secure this vital intermediate for your chemical synthesis needs.