For professionals in the pharmaceutical and fine chemical sectors, the ability to procure high-purity intermediates is critical for successful R&D and manufacturing. One such compound, (2R,3R)-2,3-Bis[(4-methylbenzoyl)oxy]succinic acid compd. with (3R,4R)-N,4-dimethyl-1-(phenylmethyl)-3-piperidinamine (CAS 477600-71-8), demands careful consideration during the purchasing process. As a vital component in the synthesis of Tofacitinib, its quality directly impacts the efficacy and safety of the final drug product.

When seeking to purchase this specific intermediate, buyers should prioritize suppliers that can guarantee high purity, typically above 95%. This is often achieved through advanced synthesis techniques and rigorous quality control measures. Working with a chemical manufacturer that specializes in chiral synthesis is often beneficial, as the stereochemistry of CAS 477600-71-8 is critical for its intended pharmaceutical application. Requesting detailed specifications, including enantiomeric excess (EE) data, is a standard practice for ensuring the correct compound is obtained.

The global market offers various options for purchasing this intermediate, with a significant number of manufacturers located in China. These suppliers often provide competitive pricing, especially for bulk orders, making them attractive partners for companies looking to optimize their procurement costs. To secure the best price, it is advisable to solicit quotes from multiple suppliers and compare not only the cost per kilogram but also the terms of sale, lead times, and shipping options. Understanding the total cost of ownership, including potential import duties and taxes, is also important when making a purchase decision.

For those looking to purchase CAS 477600-71-8, engaging with a supplier that offers custom synthesis services can also be a strategic advantage. This is particularly relevant if specific batch sizes or slight modifications to the compound's specifications are required. By establishing a relationship with a reputable manufacturer, procurement managers can ensure a consistent and reliable supply of this essential pharmaceutical intermediate, facilitating uninterrupted production and continued innovation in drug development.