Beta-D-Ribofuranose 1,2,3,5-tetraacetate (CAS 13035-61-5) stands out as a pivotal compound in the realm of organic synthesis, particularly within the pharmaceutical industry. Its structure, a protected form of ribose, makes it an invaluable intermediate for creating complex biomolecules. Understanding its synthesis, properties, and applications is fundamental for chemists and manufacturers seeking reliable building blocks for advanced pharmaceutical agents.

The synthesis of Beta-D-Ribofuranose 1,2,3,5-tetraacetate typically involves the acetylation of D-ribose or its derivatives. Common methods often start with readily available materials like inosine, which undergoes degradation and acylation reactions. The process generally utilizes acetic anhydride, often in the presence of a catalyst, to achieve the tetraacetylation. Manufacturers in China and globally employ variations of these methods to ensure high purity and yield, meeting the stringent demands of the pharmaceutical sector. The outcome is a stable, crystalline powder that is easier to handle and store than its unprotected counterpart.

The chemical properties of Beta-D-Ribofuranose 1,2,3,5-tetraacetate are key to its utility. With the formula C13H18O9, it has a molecular weight of 318.28. The presence of acetyl groups provides significant advantages: they act as protecting groups for the hydroxyl functionalities, preventing unwanted reactions during synthesis. Furthermore, these groups increase the lipophilicity of the molecule, improving its solubility in organic solvents, which is crucial for many reaction environments. This enhanced solubility and stability allow for more controlled and efficient chemical transformations, making it a preferred choice for complex synthesis pathways.

The most prominent application of Beta-D-Ribofuranose 1,2,3,5-tetraacetate is its indispensable role in the synthesis of ribavirin, a broad-spectrum antiviral drug. By acting as a key intermediate, it facilitates the complex multi-step process required to produce this vital medication. Beyond ribavirin, the compound serves as a versatile starting material for a wide array of nucleosides and other carbohydrate-based compounds. Researchers utilize it to investigate glycosylation mechanisms, develop novel drug candidates, and probe biological processes at the molecular level. Companies looking to source this compound often search for competitive pricing by exploring options to buy Beta-D-Ribofuranose 1,2,3,5-tetraacetate and compare wholesale prices from various suppliers.

NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying high-quality Beta-D-Ribofuranose 1,2,3,5-tetraacetate, ensuring that our clients in the pharmaceutical and research sectors have access to a reliable and pure intermediate. Our advanced manufacturing capabilities and commitment to quality control enable us to meet the diverse needs of the industry. We understand that for critical pharmaceutical intermediate CAS 13035-61-5, consistency and adherence to standards are non-negotiable. Partnering with NINGBO INNO PHARMCHEM CO.,LTD. ensures access to an essential acetylated ribose chemical that drives innovation in drug discovery and production.