Navigating the Synthesis of Zofenopril: A Key Pharmaceutical Intermediate
In the complex world of pharmaceutical manufacturing, the quality and availability of key intermediates are paramount. For drugs targeting cardiovascular health, such as Zofenopril, one such vital building block is cis-4-Phenylthio-L-proline Hydrochloride (CAS: 105107-84-4). Understanding this compound is crucial for procurement managers and R&D scientists seeking reliable sourcing and optimal synthesis pathways.
cis-4-Phenylthio-L-proline Hydrochloride is a high-purity chemical intermediate, typically appearing as a white powder. Its molecular formula is C11H14ClNO2S, with a molecular weight of 259.752. The emphasis on high purity, often assaying ≥98.0%, is non-negotiable in pharmaceutical applications, ensuring that the final Active Pharmaceutical Ingredient (API) meets all regulatory and efficacy standards. As a reputable manufacturer based in China, we specialize in providing this intermediate with consistent quality, catering to the demands of the global pharmaceutical industry.
The primary significance of cis-4-Phenylthio-L-proline Hydrochloride lies in its role as a precursor to Zofenopril calcium (CAS: 81938-43-4). Zofenopril is a potent angiotensin-converting enzyme (ACE) inhibitor widely prescribed for the treatment of hypertension. The precise stereochemistry of cis-4-Phenylthio-L-proline Hydrochloride is critical for the stereoselective synthesis of Zofenopril, making its quality directly impact the therapeutic effectiveness and safety profile of the final drug product. Therefore, identifying a dependable supplier for this chemical intermediate is a strategic decision for any pharmaceutical company.
For procurement professionals, sourcing from China offers distinct advantages. The country has emerged as a global hub for chemical synthesis and manufacturing, providing access to a vast network of producers capable of supplying high-quality pharmaceutical intermediates like cis-4-Phenylthio-L-proline Hydrochloride at competitive prices. When looking to buy this compound, it's essential to partner with manufacturers who can demonstrate rigorous quality control processes, adherence to international standards, and a stable supply chain. We pride ourselves on being such a manufacturer, offering not just a product, but a commitment to reliability and excellence.
The logistical aspects of handling this intermediate are also important. It is typically packaged in 25 kg drums and requires storage in a cool, ventilated place to maintain its stability and purity. For those involved in process development or large-scale manufacturing, understanding these requirements ensures seamless integration into their existing workflows. If you are searching for a supplier or looking to purchase cis-4-Phenylthio-L-proline Hydrochloride for your pharmaceutical synthesis needs, exploring options from reputable Chinese manufacturers is a prudent step. Engaging with us means you are engaging with a manufacturer dedicated to supporting your success through superior quality intermediates and responsive service.
Perspectives & Insights
Nano Explorer 01
“In the complex world of pharmaceutical manufacturing, the quality and availability of key intermediates are paramount.”
Data Catalyst One
“For drugs targeting cardiovascular health, such as Zofenopril, one such vital building block is cis-4-Phenylthio-L-proline Hydrochloride (CAS: 105107-84-4).”
Chem Thinker Labs
“Understanding this compound is crucial for procurement managers and R&D scientists seeking reliable sourcing and optimal synthesis pathways.”