Isoliquiritigenin, identified by CAS number 961-29-5, is a naturally occurring chalcone derived from the roots of *Glycyrrhiza glabra*. In recent years, this compound has garnered significant attention within the scientific community for its multifaceted pharmacological properties, particularly its profound neuroprotective capabilities. For researchers and procurement managers in the pharmaceutical and chemical industries, understanding the therapeutic potential and sourcing reliable Isoliquiritigenin manufacturers is paramount.

A key mechanism behind Isoliquiritigenin's neuroprotective action lies in its potent inhibition of human monoamine oxidase (hMAO) enzymes. Specifically, studies indicate it acts as a competitive inhibitor for hMAO-A and a mixed inhibitor for hMAO-B. Monoamine oxidases are critical in the breakdown of neurotransmitters like dopamine, serotonin, and norepinephrine. By inhibiting these enzymes, Isoliquiritigenin can help maintain optimal neurotransmitter levels, which is crucial for managing conditions like Parkinson's disease, where dopamine deficiency is a hallmark. For those looking to buy Isoliquiritigenin CAS 961-29-5, this MAO inhibitory activity makes it a compound of great interest for drug development targeting neurodegenerative disorders.

Beyond MAO inhibition, Isoliquiritigenin has demonstrated significant interactions with crucial neurotransmitter receptors. Research shows it acts as an antagonist for the dopamine D1 receptor and as an agonist for dopamine D3 and vasopressin V1A receptors. These modulatory effects on key neuronal pathways suggest its potential to ameliorate symptoms associated with Parkinson's disease, such as motor deficits, depression, and anxiety. The ability of a single compound to influence multiple targets, a characteristic of Isoliquiritigenin, aligns perfectly with modern drug discovery strategies aiming for comprehensive therapeutic benefits.

The anti-inflammatory and antioxidant properties of Isoliquiritigenin further enhance its therapeutic profile. It has been shown to protect cells from oxidative stress, reduce inflammatory responses by attenuating NF-kappaB signaling, and protect hepatic tissues from damage. These attributes make it a valuable intermediate for developing treatments for a wide range of conditions beyond neurodegenerative diseases.

For procurement managers and R&D scientists seeking to purchase high purity Isoliquiritigenin, partnering with a reputable Isoliquiritigenin manufacturer in China is essential. NINGBO INNO PHARMCHEM CO.,LTD. offers high-quality Isoliquiritigenin, ensuring the purity and consistency required for advanced research and pharmaceutical applications. By leveraging our expertise and commitment to quality, you can secure a reliable supply of this vital chemical intermediate, facilitating your drug discovery endeavors. Contact us today to inquire about Isoliquiritigenin price and availability.