N-Hydroxysuccinimide Ester Chemistry: The Power of Boc-aminooxyacetic Acid Derivative
The reactivity of N-hydroxysuccinimide (NHS) esters is a cornerstone of modern bioconjugation and chemical modification techniques. Among the various NHS esters available, Boc-aminooxyacetic acid N-hydroxysuccinimide ester (CAS: 80366-85-4) offers a unique combination of features that make it particularly valuable for sophisticated chemical applications. NINGBO INNO PHARMCHEM CO.,LTD. is a trusted supplier of this specialized derivative, supporting a wide range of scientific endeavors.
The fundamental reactivity of an NHS ester lies in its ability to undergo nucleophilic acyl substitution with primary amines. This reaction efficiently forms stable amide bonds, a common and robust linkage in organic chemistry and biochemistry. The Boc-aminooxyacetic acid portion of the molecule provides a protected aminooxy group, which can be used for specific conjugation strategies or subsequently deprotected and functionalized. This makes it a powerful tool for researchers aiming to modify biomolecules or construct complex molecular architectures. Many researchers start by looking for a reliable boc-aoa-osu supplier to source this reagent.
The utility of this specific NHS ester extends to areas such as peptide synthesis and protein labeling. In peptide synthesis, it can be used to introduce specific modifications or to create peptide conjugates with enhanced properties. For protein labeling, the rapid and efficient reaction with amine residues on proteins allows for the attachment of various tags, probes, or therapeutic payloads. The quest for advanced bioconjugation chemical solutions often leads to the selection of such well-characterized reagents. Those planning experiments will want to know the aminooxyacetic acid n-hydroxysuccinimide ester price for budgeting.
The presence of the Boc protecting group is crucial for controlling the reactivity of the aminooxy moiety. This protection allows chemists to perform other reactions on the molecule or its conjugate without premature reaction of the aminooxy group. Once the desired modifications are complete, the Boc group can be removed under specific conditions, liberating the free amino group for further chemistry. This strategic protection and deprotection are key in complex synthetic pathways. Researchers who need to buy Boc-aminooxyacetic acid N-hydroxysuccinimide ester are often seeking this level of control.
As a significant medicinal chemistry intermediate, this compound is instrumental in the development of new pharmaceuticals and research tools. Its predictable reactivity and the versatile functionalities it enables make it a valuable asset for scientists working at the intersection of chemistry and biology. NINGBO INNO PHARMCHEM CO.,LTD.'s commitment to providing high-quality chemical reagents ensures that these critical research efforts can proceed with confidence and efficiency, driving progress in chemical biology and therapeutic development.
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Future Origin 2025
“As a significant medicinal chemistry intermediate, this compound is instrumental in the development of new pharmaceuticals and research tools.”
Core Analyst 01
“Its predictable reactivity and the versatile functionalities it enables make it a valuable asset for scientists working at the intersection of chemistry and biology.”
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