The octanol-water partition coefficient (log P) is a fundamental parameter in pharmacology, toxicology, and environmental science, crucial for predicting the behavior of chemical substances in biological systems and the environment. At its core is 1-Octanol (CAS 111-87-5), a universally accepted solvent for determining this critical ratio. For researchers and pharmaceutical developers, securing a reliable source of high-purity 1-Octanol is paramount for accurate and reproducible studies.

The octanol-water partition coefficient quantifies a compound's lipophilicity (fat-loving) versus hydrophilicity (water-loving). 1-Octanol is chosen because its properties mimic biological lipid membranes to a reasonable degree, making it an excellent surrogate for predicting how a drug or chemical might partition between aqueous environments (like the cytosol) and lipid-rich environments (like cell membranes or fatty tissues). A higher log P value generally indicates greater lipophilicity, suggesting a compound may more readily cross cell membranes or accumulate in fatty tissues. Understanding this is key for anyone looking to buy 1-octanol for research and development.

For accurate log P measurements, the purity of the 1-Octanol used is critical. Impurities can skew the partitioning results, leading to erroneous conclusions. Therefore, researchers often seek 1-Octanol with assay values of 99% or higher, typically meeting specifications for analytical or chromatographic use. Identifying a trusted 1-octanol supplier that provides consistent quality and detailed Certificates of Analysis is essential for scientific integrity.

When procuring 1-Octanol for log P determination, consider manufacturers with a strong reputation in supplying high-purity reagents. Many reputable chemical companies, including those in China, offer high-grade 1-Octanol. Investigating the 1-octanol price in relation to the required purity and quantity is a standard procurement practice. Ensuring that the supplier can guarantee lot-to-lot consistency is also vital for long-term research projects.

In summary, 1-Octanol (CAS 111-87-5) is an indispensable tool for understanding lipophilicity through the octanol-water partition coefficient. Scientists and developers who need to perform these critical analyses must prioritize sourcing high-purity 1-Octanol from reliable 1-octanol manufacturers to ensure the validity of their research and development efforts.